Total antioxidant capacity of human blood plasma from healthy adults

Lipińska, S. ; Gorąca, A. ; Nowak, D.

Oxford, UK : Blackwell Publishing Ltd
Published 2003
ISSN:
1471-4159
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Reactive oxygen species are produced as a consequence of normal aerobic metabolism and could be important causative agents of a number of human diseases. Human serum contains many different antioxidants that may have importance of maintenance of antioxidant screen. Blood samples were obtained from healthy volunteers, at young (20–35 years) and old (36–60 years) age. Plasma was prepared and assayed within 3 h from blood collection and analyzed for the antioxidant capacity. At a low pH a ferric tripyridyltriazine (Fe3+-TPTZ) complex is reduced to the ferrous (Fe2+) form that causes changes of sample absorbance at 593 nm. The plasma antioxidant capacity of young and old group corresponded to 22.69 ± 0.86 and 17.59 ± 1.17 μmol of Trolox (a water-soluble analog of vitamin E). Young group had significantly higher ferric reducing/antioxidant power value than old subjects. These suggest that plasma antioxidant capacity declines with volunteers age.Acknowledgement:  The study was financed by a 502-11-809 Med. Univ. grant.
Type of Medium:
Electronic Resource
URL:
_version_ 1798290003500990464
autor Lipińska, S.
Gorąca, A.
Nowak, D.
book_url http://dx.doi.org/10.1046/j.1471-4159.85.s2.19_11.x
datenlieferant nat_lic_papers
hauptsatz hsatz_simple
identnr NLZ243129564
insertion_date 2012-04-27
issn 1471-4159
journal_name Journal of neurochemistry
materialart 1
notes Reactive oxygen species are produced as a consequence of normal aerobic metabolism and could be important causative agents of a number of human diseases. Human serum contains many different antioxidants that may have importance of maintenance of antioxidant screen. Blood samples were obtained from healthy volunteers, at young (20–35 years) and old (36–60 years) age. Plasma was prepared and assayed within 3 h from blood collection and analyzed for the antioxidant capacity. At a low pH a ferric tripyridyltriazine (Fe3+-TPTZ) complex is reduced to the ferrous (Fe2+) form that causes changes of sample absorbance at 593 nm. The plasma antioxidant capacity of young and old group corresponded to 22.69 ± 0.86 and 17.59 ± 1.17 μmol of Trolox (a water-soluble analog of vitamin E). Young group had significantly higher ferric reducing/antioxidant power value than old subjects. These suggest that plasma antioxidant capacity declines with volunteers age.Acknowledgement:  The study was financed by a 502-11-809 Med. Univ. grant.
package_name Blackwell Publishing
publikationsjahr_anzeige 2003
publikationsjahr_facette 2003
publikationsjahr_intervall 7999:2000-2004
publikationsjahr_sort 2003
publikationsort Oxford, UK
publisher Blackwell Publishing Ltd
reference 85 (2003), S. 0
search_space articles
shingle_author_1 Lipińska, S.
Gorąca, A.
Nowak, D.
shingle_author_2 Lipińska, S.
Gorąca, A.
Nowak, D.
shingle_author_3 Lipińska, S.
Gorąca, A.
Nowak, D.
shingle_author_4 Lipińska, S.
Gorąca, A.
Nowak, D.
shingle_catch_all_1 Lipińska, S.
Gorąca, A.
Nowak, D.
Total antioxidant capacity of human blood plasma from healthy adults
Blackwell Publishing Ltd
Reactive oxygen species are produced as a consequence of normal aerobic metabolism and could be important causative agents of a number of human diseases. Human serum contains many different antioxidants that may have importance of maintenance of antioxidant screen. Blood samples were obtained from healthy volunteers, at young (20–35 years) and old (36–60 years) age. Plasma was prepared and assayed within 3 h from blood collection and analyzed for the antioxidant capacity. At a low pH a ferric tripyridyltriazine (Fe3+-TPTZ) complex is reduced to the ferrous (Fe2+) form that causes changes of sample absorbance at 593 nm. The plasma antioxidant capacity of young and old group corresponded to 22.69 ± 0.86 and 17.59 ± 1.17 μmol of Trolox (a water-soluble analog of vitamin E). Young group had significantly higher ferric reducing/antioxidant power value than old subjects. These suggest that plasma antioxidant capacity declines with volunteers age.Acknowledgement:  The study was financed by a 502-11-809 Med. Univ. grant.
1471-4159
14714159
shingle_catch_all_2 Lipińska, S.
Gorąca, A.
Nowak, D.
Total antioxidant capacity of human blood plasma from healthy adults
Blackwell Publishing Ltd
Reactive oxygen species are produced as a consequence of normal aerobic metabolism and could be important causative agents of a number of human diseases. Human serum contains many different antioxidants that may have importance of maintenance of antioxidant screen. Blood samples were obtained from healthy volunteers, at young (20–35 years) and old (36–60 years) age. Plasma was prepared and assayed within 3 h from blood collection and analyzed for the antioxidant capacity. At a low pH a ferric tripyridyltriazine (Fe3+-TPTZ) complex is reduced to the ferrous (Fe2+) form that causes changes of sample absorbance at 593 nm. The plasma antioxidant capacity of young and old group corresponded to 22.69 ± 0.86 and 17.59 ± 1.17 μmol of Trolox (a water-soluble analog of vitamin E). Young group had significantly higher ferric reducing/antioxidant power value than old subjects. These suggest that plasma antioxidant capacity declines with volunteers age.Acknowledgement:  The study was financed by a 502-11-809 Med. Univ. grant.
1471-4159
14714159
shingle_catch_all_3 Lipińska, S.
Gorąca, A.
Nowak, D.
Total antioxidant capacity of human blood plasma from healthy adults
Blackwell Publishing Ltd
Reactive oxygen species are produced as a consequence of normal aerobic metabolism and could be important causative agents of a number of human diseases. Human serum contains many different antioxidants that may have importance of maintenance of antioxidant screen. Blood samples were obtained from healthy volunteers, at young (20–35 years) and old (36–60 years) age. Plasma was prepared and assayed within 3 h from blood collection and analyzed for the antioxidant capacity. At a low pH a ferric tripyridyltriazine (Fe3+-TPTZ) complex is reduced to the ferrous (Fe2+) form that causes changes of sample absorbance at 593 nm. The plasma antioxidant capacity of young and old group corresponded to 22.69 ± 0.86 and 17.59 ± 1.17 μmol of Trolox (a water-soluble analog of vitamin E). Young group had significantly higher ferric reducing/antioxidant power value than old subjects. These suggest that plasma antioxidant capacity declines with volunteers age.Acknowledgement:  The study was financed by a 502-11-809 Med. Univ. grant.
1471-4159
14714159
shingle_catch_all_4 Lipińska, S.
Gorąca, A.
Nowak, D.
Total antioxidant capacity of human blood plasma from healthy adults
Blackwell Publishing Ltd
Reactive oxygen species are produced as a consequence of normal aerobic metabolism and could be important causative agents of a number of human diseases. Human serum contains many different antioxidants that may have importance of maintenance of antioxidant screen. Blood samples were obtained from healthy volunteers, at young (20–35 years) and old (36–60 years) age. Plasma was prepared and assayed within 3 h from blood collection and analyzed for the antioxidant capacity. At a low pH a ferric tripyridyltriazine (Fe3+-TPTZ) complex is reduced to the ferrous (Fe2+) form that causes changes of sample absorbance at 593 nm. The plasma antioxidant capacity of young and old group corresponded to 22.69 ± 0.86 and 17.59 ± 1.17 μmol of Trolox (a water-soluble analog of vitamin E). Young group had significantly higher ferric reducing/antioxidant power value than old subjects. These suggest that plasma antioxidant capacity declines with volunteers age.Acknowledgement:  The study was financed by a 502-11-809 Med. Univ. grant.
1471-4159
14714159
shingle_title_1 Total antioxidant capacity of human blood plasma from healthy adults
shingle_title_2 Total antioxidant capacity of human blood plasma from healthy adults
shingle_title_3 Total antioxidant capacity of human blood plasma from healthy adults
shingle_title_4 Total antioxidant capacity of human blood plasma from healthy adults
sigel_instance_filter dkfz
geomar
wilbert
ipn
albert
source_archive Blackwell Publishing Journal Backfiles 1879-2005
timestamp 2024-05-06T08:09:49.126Z
titel Total antioxidant capacity of human blood plasma from healthy adults
titel_suche Total antioxidant capacity of human blood plasma from healthy adults
topic WW-YZ
uid nat_lic_papers_NLZ243129564