Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice
Alton, E. W. F. W. ; Middleton, P. G. ; Caplen, N. J. ; Smith, S. N. ; Steel, D. M. ; Munkonge, F. M. ; Jeffery, P. K. ; Geddes, D. M. ; Hart, S. L. ; Williamson, R. ; Fasold, K. I. ; Miller, A. D. ; Dickinson, P. ; Stevenson, B. J. ; McLachlan, G. ; Dorin, J. R. ; Porteous, D. J.
[s.l.] : Nature Publishing Group
Published 1993
[s.l.] : Nature Publishing Group
Published 1993
| ISSN: |
1546-1718
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|---|---|
| Source: |
Nature Archives 1869 - 2009
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| Topics: |
Biology
Medicine
|
| Notes: |
[Auszug] We report gene transfer to the Edinburgh insertional mutant mouse (cf/cf), delivering CFTR cDNA–liposome complexes into the airways by nebulization. We show full restoration of cAMP related chloride responses in some animals and demonstrate, in the same tissues, human CFTR cDNA expression. ...
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| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798293144453775362 |
|---|---|
| autor | Alton, E. W. F. W. Middleton, P. G. Caplen, N. J. Smith, S. N. Steel, D. M. Munkonge, F. M. Jeffery, P. K. Geddes, D. M. Hart, S. L. Williamson, R. Fasold, K. I. Miller, A. D. Dickinson, P. Stevenson, B. J. McLachlan, G. Dorin, J. R. Porteous, D. J. |
| autorsonst | Alton, E. W. F. W. Middleton, P. G. Caplen, N. J. Smith, S. N. Steel, D. M. Munkonge, F. M. Jeffery, P. K. Geddes, D. M. Hart, S. L. Williamson, R. Fasold, K. I. Miller, A. D. Dickinson, P. Stevenson, B. J. McLachlan, G. Dorin, J. R. Porteous, D. J. |
| book_url | http://dx.doi.org/10.1038/ng1093-135 |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLZ231722982 |
| insertion_date | 1911-02-24 |
| iqvoc_descriptor_title | iqvoc_00000124:transport |
| issn | 1546-1718 |
| journal_name | Nature genetics |
| materialart | 1 |
| notes | [Auszug] We report gene transfer to the Edinburgh insertional mutant mouse (cf/cf), delivering CFTR cDNA–liposome complexes into the airways by nebulization. We show full restoration of cAMP related chloride responses in some animals and demonstrate, in the same tissues, human CFTR cDNA expression. ... |
| package_name | Nature Publishing Group |
| publikationsjahr_anzeige | 1993 |
| publikationsjahr_facette | 1993 |
| publikationsjahr_intervall | 8009:1990-1994 |
| publikationsjahr_sort | 1993 |
| publikationsort | [s.l.] |
| publisher | Nature Publishing Group |
| reference | 5 (1993), S. 135-142 |
| search_space | articles |
| shingle_author_1 | Alton, E. W. F. W. Middleton, P. G. Caplen, N. J. Smith, S. N. Steel, D. M. Munkonge, F. M. Jeffery, P. K. Geddes, D. M. Hart, S. L. Williamson, R. Fasold, K. I. Miller, A. D. Dickinson, P. Stevenson, B. J. McLachlan, G. Dorin, J. R. Porteous, D. J. |
| shingle_author_2 | Alton, E. W. F. W. Middleton, P. G. Caplen, N. J. Smith, S. N. Steel, D. M. Munkonge, F. M. Jeffery, P. K. Geddes, D. M. Hart, S. L. Williamson, R. Fasold, K. I. Miller, A. D. Dickinson, P. Stevenson, B. J. McLachlan, G. Dorin, J. R. Porteous, D. J. |
| shingle_author_3 | Alton, E. W. F. W. Middleton, P. G. Caplen, N. J. Smith, S. N. Steel, D. M. Munkonge, F. M. Jeffery, P. K. Geddes, D. M. Hart, S. L. Williamson, R. Fasold, K. I. Miller, A. D. Dickinson, P. Stevenson, B. J. McLachlan, G. Dorin, J. R. Porteous, D. J. |
| shingle_author_4 | Alton, E. W. F. W. Middleton, P. G. Caplen, N. J. Smith, S. N. Steel, D. M. Munkonge, F. M. Jeffery, P. K. Geddes, D. M. Hart, S. L. Williamson, R. Fasold, K. I. Miller, A. D. Dickinson, P. Stevenson, B. J. McLachlan, G. Dorin, J. R. Porteous, D. J. |
| shingle_catch_all_1 | Alton, E. W. F. W. Middleton, P. G. Caplen, N. J. Smith, S. N. Steel, D. M. Munkonge, F. M. Jeffery, P. K. Geddes, D. M. Hart, S. L. Williamson, R. Fasold, K. I. Miller, A. D. Dickinson, P. Stevenson, B. J. McLachlan, G. Dorin, J. R. Porteous, D. J. Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice Nature Publishing Group [Auszug] We report gene transfer to the Edinburgh insertional mutant mouse (cf/cf), delivering CFTR cDNA–liposome complexes into the airways by nebulization. We show full restoration of cAMP related chloride responses in some animals and demonstrate, in the same tissues, human CFTR cDNA expression. ... 1546-1718 15461718 |
| shingle_catch_all_2 | Alton, E. W. F. W. Middleton, P. G. Caplen, N. J. Smith, S. N. Steel, D. M. Munkonge, F. M. Jeffery, P. K. Geddes, D. M. Hart, S. L. Williamson, R. Fasold, K. I. Miller, A. D. Dickinson, P. Stevenson, B. J. McLachlan, G. Dorin, J. R. Porteous, D. J. Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice Nature Publishing Group [Auszug] We report gene transfer to the Edinburgh insertional mutant mouse (cf/cf), delivering CFTR cDNA–liposome complexes into the airways by nebulization. We show full restoration of cAMP related chloride responses in some animals and demonstrate, in the same tissues, human CFTR cDNA expression. ... 1546-1718 15461718 |
| shingle_catch_all_3 | Alton, E. W. F. W. Middleton, P. G. Caplen, N. J. Smith, S. N. Steel, D. M. Munkonge, F. M. Jeffery, P. K. Geddes, D. M. Hart, S. L. Williamson, R. Fasold, K. I. Miller, A. D. Dickinson, P. Stevenson, B. J. McLachlan, G. Dorin, J. R. Porteous, D. J. Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice Nature Publishing Group [Auszug] We report gene transfer to the Edinburgh insertional mutant mouse (cf/cf), delivering CFTR cDNA–liposome complexes into the airways by nebulization. We show full restoration of cAMP related chloride responses in some animals and demonstrate, in the same tissues, human CFTR cDNA expression. ... 1546-1718 15461718 |
| shingle_catch_all_4 | Alton, E. W. F. W. Middleton, P. G. Caplen, N. J. Smith, S. N. Steel, D. M. Munkonge, F. M. Jeffery, P. K. Geddes, D. M. Hart, S. L. Williamson, R. Fasold, K. I. Miller, A. D. Dickinson, P. Stevenson, B. J. McLachlan, G. Dorin, J. R. Porteous, D. J. Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice Nature Publishing Group [Auszug] We report gene transfer to the Edinburgh insertional mutant mouse (cf/cf), delivering CFTR cDNA–liposome complexes into the airways by nebulization. We show full restoration of cAMP related chloride responses in some animals and demonstrate, in the same tissues, human CFTR cDNA expression. ... 1546-1718 15461718 |
| shingle_title_1 | Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice |
| shingle_title_2 | Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice |
| shingle_title_3 | Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice |
| shingle_title_4 | Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice |
| sigel_instance_filter | dkfz geomar wilbert ipn albert |
| source_archive | Nature Archives 1869 - 2009 |
| timestamp | 2024-05-06T08:59:44.803Z |
| titel | Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice |
| titel_suche | Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice |
| topic | W WW-YZ |
| uid | nat_lic_papers_NLZ231722982 |