Inhibition of platelet secretion of ATP by phalloidin
| ISSN: |
0309-1651
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|---|---|
| Source: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
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| Topics: |
Biology
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| Type of Medium: |
Electronic Resource
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| URL: |
| _version_ | 1798291881996582912 |
|---|---|
| autor | Hashimoto, K. Kawarabayashi, K. Hashimoto, K. Tatsumi, N. |
| autorsonst | Hashimoto, K. Kawarabayashi, K. Hashimoto, K. Tatsumi, N. |
| book_url | http://dx.doi.org/10.1016/0309-1651(86)90018-4 |
| datenlieferant | nat_lic_papers |
| fussnote | The involvement of actin in the secretion of ATP by platelets was studied using two stimulants, ADP and A23187, and two actin-mediating reagents, cytochalasin B and phalloidin. The degree of actin polymerization was determined using DNase I.Preincubation of platelets with cytochalasin B suppressed the polymerization of actin and ATP secretion induced by stimulants. In the absence of the stimulant, phalloidin-treated platelets exhibited time-dependent actin polymerization and the maximum level was reached at 5 min. No secretion of ATP was observed.The polymerization was enhanced by phalloidin when the platelets were preincubated for 3 to 5 min with the stimulants, but little ATP was secreted. After a 30-min preincubation, the amount of polymerized actin was lower than that after a 5-min incubation, and no ATP was secreted. |
| hauptsatz | hsatz_simple |
| identnr | NLZ183769007 |
| issn | 0309-1651 |
| journal_name | Cell Biology International Reports |
| materialart | 1 |
| package_name | Elsevier |
| publikationsort | Amsterdam |
| publisher | Elsevier |
| reference | 10 (1986), S. 41-47 |
| search_space | articles |
| shingle_author_1 | Hashimoto, K. Kawarabayashi, K. Hashimoto, K. Tatsumi, N. |
| shingle_author_2 | Hashimoto, K. Kawarabayashi, K. Hashimoto, K. Tatsumi, N. |
| shingle_author_3 | Hashimoto, K. Kawarabayashi, K. Hashimoto, K. Tatsumi, N. |
| shingle_author_4 | Hashimoto, K. Kawarabayashi, K. Hashimoto, K. Tatsumi, N. |
| shingle_catch_all_1 | Hashimoto, K. Kawarabayashi, K. Hashimoto, K. Tatsumi, N. Inhibition of platelet secretion of ATP by phalloidin 0309-1651 03091651 Elsevier |
| shingle_catch_all_2 | Hashimoto, K. Kawarabayashi, K. Hashimoto, K. Tatsumi, N. Inhibition of platelet secretion of ATP by phalloidin 0309-1651 03091651 Elsevier |
| shingle_catch_all_3 | Hashimoto, K. Kawarabayashi, K. Hashimoto, K. Tatsumi, N. Inhibition of platelet secretion of ATP by phalloidin 0309-1651 03091651 Elsevier |
| shingle_catch_all_4 | Hashimoto, K. Kawarabayashi, K. Hashimoto, K. Tatsumi, N. Inhibition of platelet secretion of ATP by phalloidin 0309-1651 03091651 Elsevier |
| shingle_title_1 | Inhibition of platelet secretion of ATP by phalloidin |
| shingle_title_2 | Inhibition of platelet secretion of ATP by phalloidin |
| shingle_title_3 | Inhibition of platelet secretion of ATP by phalloidin |
| shingle_title_4 | Inhibition of platelet secretion of ATP by phalloidin |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
| timestamp | 2024-05-06T08:39:41.241Z |
| titel | Inhibition of platelet secretion of ATP by phalloidin |
| titel_suche | Inhibition of platelet secretion of ATP by phalloidin The involvement of actin in the secretion of ATP by platelets was studied using two stimulants, ADP and A23187, and two actin-mediating reagents, cytochalasin B and phalloidin. The degree of actin polymerization was determined using DNase I.Preincubation of platelets with cytochalasin B suppressed the polymerization of actin and ATP secretion induced by stimulants. In the absence of the stimulant, phalloidin-treated platelets exhibited time-dependent actin polymerization and the maximum level was reached at 5 min. No secretion of ATP was observed.The polymerization was enhanced by phalloidin when the platelets were preincubated for 3 to 5 min with the stimulants, but little ATP was secreted. After a 30-min preincubation, the amount of polymerized actin was lower than that after a 5-min incubation, and no ATP was secreted. |
| topic | W |
| uid | nat_lic_papers_NLZ183769007 |