Isochores and CpG Islands in YAC Contigs in Human Xq26.1-qter

ISSN:
0888-7543
Source:
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:
Biology
Medicine
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1006/geno.1993.1347
_version_ 1798292083463684096
autor Pilia, G.
Little, R.D.
Aissani, B.
Bernardi, G.
Schlessinger, D.
autorsonst Pilia, G.
Little, R.D.
Aissani, B.
Bernardi, G.
Schlessinger, D.
book_url http://dx.doi.org/10.1006/geno.1993.1347
datenlieferant nat_lic_papers
fussnote GC levels were assessed at 37 loci across 30 Mb of Xq26.1-qter, a region physically mopped in overlapping yeast artificial chromosome clones. In 8 Mb of R band Xq26, GC is relatively high (up to 44%) in the proximal 4 Mb and relatively low (40-41%) in the distal 4 Mb. Consistently low GC values (38-41%) are observed in G band Xq27. In contrast, further toward the telomere in Xq28, the GC level rises progressively to reach 52% at 2 to 4 Mb from the end of the chromosome; this region is delimited by low GC loci. Across these regions of Xq, the content of rare-cutter restriction enzyme sites containing CpG, including 'CpG islands' in the most completely mapped Xq26-27.1 region, is correlated with GC level. Isochore mapping can thus provide one index of putative gene content across mapped regions.
hauptsatz hsatz_simple
identnr NLZ183735269
issn 0888-7543
journal_name Genomics
materialart 1
package_name Elsevier
publikationsort Amsterdam
publisher Elsevier
reference 17 (1993), S. 456-462
search_space articles
shingle_author_1 Pilia, G.
Little, R.D.
Aissani, B.
Bernardi, G.
Schlessinger, D.
shingle_author_2 Pilia, G.
Little, R.D.
Aissani, B.
Bernardi, G.
Schlessinger, D.
shingle_author_3 Pilia, G.
Little, R.D.
Aissani, B.
Bernardi, G.
Schlessinger, D.
shingle_author_4 Pilia, G.
Little, R.D.
Aissani, B.
Bernardi, G.
Schlessinger, D.
shingle_catch_all_1 Pilia, G.
Little, R.D.
Aissani, B.
Bernardi, G.
Schlessinger, D.
Isochores and CpG Islands in YAC Contigs in Human Xq26.1-qter
0888-7543
08887543
Elsevier
shingle_catch_all_2 Pilia, G.
Little, R.D.
Aissani, B.
Bernardi, G.
Schlessinger, D.
Isochores and CpG Islands in YAC Contigs in Human Xq26.1-qter
0888-7543
08887543
Elsevier
shingle_catch_all_3 Pilia, G.
Little, R.D.
Aissani, B.
Bernardi, G.
Schlessinger, D.
Isochores and CpG Islands in YAC Contigs in Human Xq26.1-qter
0888-7543
08887543
Elsevier
shingle_catch_all_4 Pilia, G.
Little, R.D.
Aissani, B.
Bernardi, G.
Schlessinger, D.
Isochores and CpG Islands in YAC Contigs in Human Xq26.1-qter
0888-7543
08887543
Elsevier
shingle_title_1 Isochores and CpG Islands in YAC Contigs in Human Xq26.1-qter
shingle_title_2 Isochores and CpG Islands in YAC Contigs in Human Xq26.1-qter
shingle_title_3 Isochores and CpG Islands in YAC Contigs in Human Xq26.1-qter
shingle_title_4 Isochores and CpG Islands in YAC Contigs in Human Xq26.1-qter
sigel_instance_filter dkfz
geomar
wilbert
ipn
albert
fhp
source_archive Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
timestamp 2024-05-06T08:42:53.297Z
titel Isochores and CpG Islands in YAC Contigs in Human Xq26.1-qter
titel_suche Isochores and CpG Islands in YAC Contigs in Human Xq26.1-qter
GC levels were assessed at 37 loci across 30 Mb of Xq26.1-qter, a region physically mopped in overlapping yeast artificial chromosome clones. In 8 Mb of R band Xq26, GC is relatively high (up to 44%) in the proximal 4 Mb and relatively low (40-41%) in the distal 4 Mb. Consistently low GC values (38-41%) are observed in G band Xq27. In contrast, further toward the telomere in Xq28, the GC level rises progressively to reach 52% at 2 to 4 Mb from the end of the chromosome; this region is delimited by low GC loci. Across these regions of Xq, the content of rare-cutter restriction enzyme sites containing CpG, including 'CpG islands' in the most completely mapped Xq26-27.1 region, is correlated with GC level. Isochore mapping can thus provide one index of putative gene content across mapped regions.
topic W
WW-YZ
uid nat_lic_papers_NLZ183735269