Solubility of the antibiotic penicillin V in supercritical CO"2

Ko, M. ; Shah, V. ; Bienkowski, P.R. ; Cochran, H.D.

Amsterdam : Elsevier
ISSN:
0896-8446
Keywords:
antibiotic ; penicillin ; supercritical extraction
Source:
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Physics
Process Engineering, Biotechnology, Nutrition Technology
Type of Medium:
Electronic Resource
URL:
_version_ 1798292088393039873
autor Ko, M.
Shah, V.
Bienkowski, P.R.
Cochran, H.D.
autorsonst Ko, M.
Shah, V.
Bienkowski, P.R.
Cochran, H.D.
book_url http://dx.doi.org/10.1016/0896-8446(91)90028-5
datenlieferant nat_lic_papers
fussnote The solubility of the antibiotic penicillin V in C0"2 has been measured at temperature from 314.85 K to 334.85 K and pressures form 7.987 MPa to 28.02 MPa using a dynamic flow apparatus. The equilibrium mole fraction in this region ranged from 6.2 x 10^-^5 to 5.7 x 10^-^4, which 9is about 10^6 to 10^8 times the ideal gas solubility. The vapor pressure of penicillin V, which has not been reported in the literature, was estimated from the solubility data so the latter could be correlated. Other unknown physical properties of penicillin V were estimated using group contribution methods. The experimental solubility data were correlated using a compressed gas model with the Peng-Robinson equation-of-state and a theoretical model based on Kirkwood-Buff solution theory. Solubility results are compared for this system and other complex biological molecules taken from the literature.
hauptsatz hsatz_simple
identnr NLZ18301331X
issn 0896-8446
journal_name The @Journal of Supercritical Fluids
materialart 1
package_name Elsevier
publikationsort Amsterdam
publisher Elsevier
reference 4 (1991), S. 32-39
schlagwort antibiotic
penicillin
supercritical extraction
search_space articles
shingle_author_1 Ko, M.
Shah, V.
Bienkowski, P.R.
Cochran, H.D.
shingle_author_2 Ko, M.
Shah, V.
Bienkowski, P.R.
Cochran, H.D.
shingle_author_3 Ko, M.
Shah, V.
Bienkowski, P.R.
Cochran, H.D.
shingle_author_4 Ko, M.
Shah, V.
Bienkowski, P.R.
Cochran, H.D.
shingle_catch_all_1 Ko, M.
Shah, V.
Bienkowski, P.R.
Cochran, H.D.
Solubility of the antibiotic penicillin V in supercritical CO"2
antibiotic
penicillin
supercritical extraction
antibiotic
penicillin
supercritical extraction
0896-8446
08968446
Elsevier
shingle_catch_all_2 Ko, M.
Shah, V.
Bienkowski, P.R.
Cochran, H.D.
Solubility of the antibiotic penicillin V in supercritical CO"2
antibiotic
penicillin
supercritical extraction
antibiotic
penicillin
supercritical extraction
0896-8446
08968446
Elsevier
shingle_catch_all_3 Ko, M.
Shah, V.
Bienkowski, P.R.
Cochran, H.D.
Solubility of the antibiotic penicillin V in supercritical CO"2
antibiotic
penicillin
supercritical extraction
antibiotic
penicillin
supercritical extraction
0896-8446
08968446
Elsevier
shingle_catch_all_4 Ko, M.
Shah, V.
Bienkowski, P.R.
Cochran, H.D.
Solubility of the antibiotic penicillin V in supercritical CO"2
antibiotic
penicillin
supercritical extraction
antibiotic
penicillin
supercritical extraction
0896-8446
08968446
Elsevier
shingle_title_1 Solubility of the antibiotic penicillin V in supercritical CO"2
shingle_title_2 Solubility of the antibiotic penicillin V in supercritical CO"2
shingle_title_3 Solubility of the antibiotic penicillin V in supercritical CO"2
shingle_title_4 Solubility of the antibiotic penicillin V in supercritical CO"2
sigel_instance_filter dkfz
geomar
wilbert
ipn
albert
fhp
source_archive Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
timestamp 2024-05-06T08:42:56.546Z
titel Solubility of the antibiotic penicillin V in supercritical CO"2
titel_suche Solubility of the antibiotic penicillin V in supercritical CO"2
The solubility of the antibiotic penicillin V in C0"2 has been measured at temperature from 314.85 K to 334.85 K and pressures form 7.987 MPa to 28.02 MPa using a dynamic flow apparatus. The equilibrium mole fraction in this region ranged from 6.2 x 10^-^5 to 5.7 x 10^-^4, which 9is about 10^6 to 10^8 times the ideal gas solubility. The vapor pressure of penicillin V, which has not been reported in the literature, was estimated from the solubility data so the latter could be correlated. Other unknown physical properties of penicillin V were estimated using group contribution methods. The experimental solubility data were correlated using a compressed gas model with the Peng-Robinson equation-of-state and a theoretical model based on Kirkwood-Buff solution theory. Solubility results are compared for this system and other complex biological molecules taken from the literature.
topic ZL
U
ZM
uid nat_lic_papers_NLZ18301331X