Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM)
Brunner, H. G. ; Korneluk, R. G. ; Coerwinkel-Driessen, M. ; MacKenzie, A. ; Smeets, H. ; Lambermon, H. M. M. ; Oost, B. A. ; Wieringa, B. ; Ropers, H. -H.
Springer
Published 1989
Springer
Published 1989
| ISSN: |
1432-1203
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Biology
Medicine
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| Notes: |
Summary We have studied genetic linkage between the gene for creatine kinase muscle type (CKMM) and the gene for myotonic dystrophy (DM). In a panel of 65 myotonic dystrophy families from Canada and the Netherlands, a maximum lod score (Zmax) of 22.8 at a recombination frequency (Θ) of 0.03 was obtained. Tight linkage was also demonstrated for CKMM and the gene for apolipoprotein C2 (ApoC2). This establishes CKMM as a useful marker for myotonic dystrophy.
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| Type of Medium: |
Electronic Resource
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| URL: |
| _version_ | 1798295622591184896 |
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| autor | Brunner, H. G. Korneluk, R. G. Coerwinkel-Driessen, M. MacKenzie, A. Smeets, H. Lambermon, H. M. M. Oost, B. A. Wieringa, B. Ropers, H. -H. |
| autorsonst | Brunner, H. G. Korneluk, R. G. Coerwinkel-Driessen, M. MacKenzie, A. Smeets, H. Lambermon, H. M. M. Oost, B. A. Wieringa, B. Ropers, H. -H. |
| book_url | http://dx.doi.org/10.1007/BF00283680 |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLM20562281X |
| issn | 1432-1203 |
| journal_name | Human genetics 〈Berlin〉 |
| materialart | 1 |
| notes | Summary We have studied genetic linkage between the gene for creatine kinase muscle type (CKMM) and the gene for myotonic dystrophy (DM). In a panel of 65 myotonic dystrophy families from Canada and the Netherlands, a maximum lod score (Zmax) of 22.8 at a recombination frequency (Θ) of 0.03 was obtained. Tight linkage was also demonstrated for CKMM and the gene for apolipoprotein C2 (ApoC2). This establishes CKMM as a useful marker for myotonic dystrophy. |
| package_name | Springer |
| publikationsjahr_anzeige | 1989 |
| publikationsjahr_facette | 1989 |
| publikationsjahr_intervall | 8014:1985-1989 |
| publikationsjahr_sort | 1989 |
| publisher | Springer |
| reference | 81 (1989), S. 308-310 |
| search_space | articles |
| shingle_author_1 | Brunner, H. G. Korneluk, R. G. Coerwinkel-Driessen, M. MacKenzie, A. Smeets, H. Lambermon, H. M. M. Oost, B. A. Wieringa, B. Ropers, H. -H. |
| shingle_author_2 | Brunner, H. G. Korneluk, R. G. Coerwinkel-Driessen, M. MacKenzie, A. Smeets, H. Lambermon, H. M. M. Oost, B. A. Wieringa, B. Ropers, H. -H. |
| shingle_author_3 | Brunner, H. G. Korneluk, R. G. Coerwinkel-Driessen, M. MacKenzie, A. Smeets, H. Lambermon, H. M. M. Oost, B. A. Wieringa, B. Ropers, H. -H. |
| shingle_author_4 | Brunner, H. G. Korneluk, R. G. Coerwinkel-Driessen, M. MacKenzie, A. Smeets, H. Lambermon, H. M. M. Oost, B. A. Wieringa, B. Ropers, H. -H. |
| shingle_catch_all_1 | Brunner, H. G. Korneluk, R. G. Coerwinkel-Driessen, M. MacKenzie, A. Smeets, H. Lambermon, H. M. M. Oost, B. A. Wieringa, B. Ropers, H. -H. Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM) Summary We have studied genetic linkage between the gene for creatine kinase muscle type (CKMM) and the gene for myotonic dystrophy (DM). In a panel of 65 myotonic dystrophy families from Canada and the Netherlands, a maximum lod score (Zmax) of 22.8 at a recombination frequency (Θ) of 0.03 was obtained. Tight linkage was also demonstrated for CKMM and the gene for apolipoprotein C2 (ApoC2). This establishes CKMM as a useful marker for myotonic dystrophy. 1432-1203 14321203 Springer |
| shingle_catch_all_2 | Brunner, H. G. Korneluk, R. G. Coerwinkel-Driessen, M. MacKenzie, A. Smeets, H. Lambermon, H. M. M. Oost, B. A. Wieringa, B. Ropers, H. -H. Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM) Summary We have studied genetic linkage between the gene for creatine kinase muscle type (CKMM) and the gene for myotonic dystrophy (DM). In a panel of 65 myotonic dystrophy families from Canada and the Netherlands, a maximum lod score (Zmax) of 22.8 at a recombination frequency (Θ) of 0.03 was obtained. Tight linkage was also demonstrated for CKMM and the gene for apolipoprotein C2 (ApoC2). This establishes CKMM as a useful marker for myotonic dystrophy. 1432-1203 14321203 Springer |
| shingle_catch_all_3 | Brunner, H. G. Korneluk, R. G. Coerwinkel-Driessen, M. MacKenzie, A. Smeets, H. Lambermon, H. M. M. Oost, B. A. Wieringa, B. Ropers, H. -H. Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM) Summary We have studied genetic linkage between the gene for creatine kinase muscle type (CKMM) and the gene for myotonic dystrophy (DM). In a panel of 65 myotonic dystrophy families from Canada and the Netherlands, a maximum lod score (Zmax) of 22.8 at a recombination frequency (Θ) of 0.03 was obtained. Tight linkage was also demonstrated for CKMM and the gene for apolipoprotein C2 (ApoC2). This establishes CKMM as a useful marker for myotonic dystrophy. 1432-1203 14321203 Springer |
| shingle_catch_all_4 | Brunner, H. G. Korneluk, R. G. Coerwinkel-Driessen, M. MacKenzie, A. Smeets, H. Lambermon, H. M. M. Oost, B. A. Wieringa, B. Ropers, H. -H. Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM) Summary We have studied genetic linkage between the gene for creatine kinase muscle type (CKMM) and the gene for myotonic dystrophy (DM). In a panel of 65 myotonic dystrophy families from Canada and the Netherlands, a maximum lod score (Zmax) of 22.8 at a recombination frequency (Θ) of 0.03 was obtained. Tight linkage was also demonstrated for CKMM and the gene for apolipoprotein C2 (ApoC2). This establishes CKMM as a useful marker for myotonic dystrophy. 1432-1203 14321203 Springer |
| shingle_title_1 | Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM) |
| shingle_title_2 | Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM) |
| shingle_title_3 | Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM) |
| shingle_title_4 | Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM) |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Springer Online Journal Archives 1860-2000 |
| timestamp | 2024-05-06T09:39:07.990Z |
| titel | Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM) |
| titel_suche | Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM) |
| topic | W WW-YZ |
| uid | nat_lic_papers_NLM20562281X |