The immune response in iron-deficient young children: Effect of iron supplementation on cell-mediated immunity
Thibault, H. ; Galan, P. ; Selz, F. ; Preziosi, P. ; Olivier, C. ; Badoual, J. ; Hercberg, S.
Springer
Published 1993
Springer
Published 1993
ISSN: |
1432-1076
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Keywords: |
Iron deficiency ; Iron supplementation ; Immune functions ; Cell-mediated immunity ; Interleukin-2
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Source: |
Springer Online Journal Archives 1860-2000
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Topics: |
Medicine
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Notes: |
Abstract The effects of iron deficiency on immunity remain controversial. This study was designed to assess the impact of iron supplementation on the immune status, in 81 children aged 6 months–3 years, at high risk for iron deficiency, using a longitudinal double blind randomised and placebo-controlled study. Lymphocytes of iron-deficient children produced less interleukin-2 in vitro. Iron supplementation for 2 months increased mean corpuscular volume, serum ferritin and serum transferrin, but had no effect on the parameters of T-cell mediated immunity. The lower interleukin-2 levels in iron-deficient suggest that cell-mediated immunity may be impaired in iron deficiency.
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Type of Medium: |
Electronic Resource
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URL: |
_version_ | 1798295578386366464 |
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autor | Thibault, H. Galan, P. Selz, F. Preziosi, P. Olivier, C. Badoual, J. Hercberg, S. |
autorsonst | Thibault, H. Galan, P. Selz, F. Preziosi, P. Olivier, C. Badoual, J. Hercberg, S. |
book_url | http://dx.doi.org/10.1007/BF02072487 |
datenlieferant | nat_lic_papers |
hauptsatz | hsatz_simple |
identnr | NLM205187218 |
issn | 1432-1076 |
journal_name | European journal of pediatrics |
materialart | 1 |
notes | Abstract The effects of iron deficiency on immunity remain controversial. This study was designed to assess the impact of iron supplementation on the immune status, in 81 children aged 6 months–3 years, at high risk for iron deficiency, using a longitudinal double blind randomised and placebo-controlled study. Lymphocytes of iron-deficient children produced less interleukin-2 in vitro. Iron supplementation for 2 months increased mean corpuscular volume, serum ferritin and serum transferrin, but had no effect on the parameters of T-cell mediated immunity. The lower interleukin-2 levels in iron-deficient suggest that cell-mediated immunity may be impaired in iron deficiency. |
package_name | Springer |
publikationsjahr_anzeige | 1993 |
publikationsjahr_facette | 1993 |
publikationsjahr_intervall | 8009:1990-1994 |
publikationsjahr_sort | 1993 |
publisher | Springer |
reference | 152 (1993), S. 120-124 |
schlagwort | Iron deficiency Iron supplementation Immune functions Cell-mediated immunity Interleukin-2 |
search_space | articles |
shingle_author_1 | Thibault, H. Galan, P. Selz, F. Preziosi, P. Olivier, C. Badoual, J. Hercberg, S. |
shingle_author_2 | Thibault, H. Galan, P. Selz, F. Preziosi, P. Olivier, C. Badoual, J. Hercberg, S. |
shingle_author_3 | Thibault, H. Galan, P. Selz, F. Preziosi, P. Olivier, C. Badoual, J. Hercberg, S. |
shingle_author_4 | Thibault, H. Galan, P. Selz, F. Preziosi, P. Olivier, C. Badoual, J. Hercberg, S. |
shingle_catch_all_1 | Thibault, H. Galan, P. Selz, F. Preziosi, P. Olivier, C. Badoual, J. Hercberg, S. The immune response in iron-deficient young children: Effect of iron supplementation on cell-mediated immunity Iron deficiency Iron supplementation Immune functions Cell-mediated immunity Interleukin-2 Iron deficiency Iron supplementation Immune functions Cell-mediated immunity Interleukin-2 Abstract The effects of iron deficiency on immunity remain controversial. This study was designed to assess the impact of iron supplementation on the immune status, in 81 children aged 6 months–3 years, at high risk for iron deficiency, using a longitudinal double blind randomised and placebo-controlled study. Lymphocytes of iron-deficient children produced less interleukin-2 in vitro. Iron supplementation for 2 months increased mean corpuscular volume, serum ferritin and serum transferrin, but had no effect on the parameters of T-cell mediated immunity. The lower interleukin-2 levels in iron-deficient suggest that cell-mediated immunity may be impaired in iron deficiency. 1432-1076 14321076 Springer |
shingle_catch_all_2 | Thibault, H. Galan, P. Selz, F. Preziosi, P. Olivier, C. Badoual, J. Hercberg, S. The immune response in iron-deficient young children: Effect of iron supplementation on cell-mediated immunity Iron deficiency Iron supplementation Immune functions Cell-mediated immunity Interleukin-2 Iron deficiency Iron supplementation Immune functions Cell-mediated immunity Interleukin-2 Abstract The effects of iron deficiency on immunity remain controversial. This study was designed to assess the impact of iron supplementation on the immune status, in 81 children aged 6 months–3 years, at high risk for iron deficiency, using a longitudinal double blind randomised and placebo-controlled study. Lymphocytes of iron-deficient children produced less interleukin-2 in vitro. Iron supplementation for 2 months increased mean corpuscular volume, serum ferritin and serum transferrin, but had no effect on the parameters of T-cell mediated immunity. The lower interleukin-2 levels in iron-deficient suggest that cell-mediated immunity may be impaired in iron deficiency. 1432-1076 14321076 Springer |
shingle_catch_all_3 | Thibault, H. Galan, P. Selz, F. Preziosi, P. Olivier, C. Badoual, J. Hercberg, S. The immune response in iron-deficient young children: Effect of iron supplementation on cell-mediated immunity Iron deficiency Iron supplementation Immune functions Cell-mediated immunity Interleukin-2 Iron deficiency Iron supplementation Immune functions Cell-mediated immunity Interleukin-2 Abstract The effects of iron deficiency on immunity remain controversial. This study was designed to assess the impact of iron supplementation on the immune status, in 81 children aged 6 months–3 years, at high risk for iron deficiency, using a longitudinal double blind randomised and placebo-controlled study. Lymphocytes of iron-deficient children produced less interleukin-2 in vitro. Iron supplementation for 2 months increased mean corpuscular volume, serum ferritin and serum transferrin, but had no effect on the parameters of T-cell mediated immunity. The lower interleukin-2 levels in iron-deficient suggest that cell-mediated immunity may be impaired in iron deficiency. 1432-1076 14321076 Springer |
shingle_catch_all_4 | Thibault, H. Galan, P. Selz, F. Preziosi, P. Olivier, C. Badoual, J. Hercberg, S. The immune response in iron-deficient young children: Effect of iron supplementation on cell-mediated immunity Iron deficiency Iron supplementation Immune functions Cell-mediated immunity Interleukin-2 Iron deficiency Iron supplementation Immune functions Cell-mediated immunity Interleukin-2 Abstract The effects of iron deficiency on immunity remain controversial. This study was designed to assess the impact of iron supplementation on the immune status, in 81 children aged 6 months–3 years, at high risk for iron deficiency, using a longitudinal double blind randomised and placebo-controlled study. Lymphocytes of iron-deficient children produced less interleukin-2 in vitro. Iron supplementation for 2 months increased mean corpuscular volume, serum ferritin and serum transferrin, but had no effect on the parameters of T-cell mediated immunity. The lower interleukin-2 levels in iron-deficient suggest that cell-mediated immunity may be impaired in iron deficiency. 1432-1076 14321076 Springer |
shingle_title_1 | The immune response in iron-deficient young children: Effect of iron supplementation on cell-mediated immunity |
shingle_title_2 | The immune response in iron-deficient young children: Effect of iron supplementation on cell-mediated immunity |
shingle_title_3 | The immune response in iron-deficient young children: Effect of iron supplementation on cell-mediated immunity |
shingle_title_4 | The immune response in iron-deficient young children: Effect of iron supplementation on cell-mediated immunity |
sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
source_archive | Springer Online Journal Archives 1860-2000 |
timestamp | 2024-05-06T09:38:26.388Z |
titel | The immune response in iron-deficient young children: Effect of iron supplementation on cell-mediated immunity |
titel_suche | The immune response in iron-deficient young children: Effect of iron supplementation on cell-mediated immunity |
topic | WW-YZ |
uid | nat_lic_papers_NLM205187218 |