An alkaline kit formulation to obtain [99mTc]MAG3 in high radiochemical yields

ISSN:
1588-2780
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Energy, Environment Protection, Nuclear Power Engineering
Notes:
Abstract An alkaline kit formulation (pH 9) to obtain [99mTc]MAG3 with radiochemical puritives over 98% has been developed, avoiding the addition of filtered air to the vial, the use of large amounts of99mTc activity (i.e., 3.7 GBq) or the reconstitution of large volumes. The use of this radiopharmaceutical in mice showed a minimal accumulation in the hepatobiliary system (0.37±0.3% I.D., 1 h postinjection). However, in rabbits we always obtained good image quality.
Type of Medium:
Electronic Resource
URL:
_version_ 1798297297696587777
autor Reyes-Herrera, L.
Ferro-Flores, G.
Lezama-Carrasco, J.
Gonzalez-Zavala, M. A.
Ureña-Nuñez, F.
Avila-Ramirez, E.
autorsonst Reyes-Herrera, L.
Ferro-Flores, G.
Lezama-Carrasco, J.
Gonzalez-Zavala, M. A.
Ureña-Nuñez, F.
Avila-Ramirez, E.
book_url http://dx.doi.org/10.1007/BF02164638
datenlieferant nat_lic_papers
hauptsatz hsatz_simple
identnr NLM194927059
issn 1588-2780
journal_name Journal of radioanalytical and nuclear chemistry
materialart 1
notes Abstract An alkaline kit formulation (pH 9) to obtain [99mTc]MAG3 with radiochemical puritives over 98% has been developed, avoiding the addition of filtered air to the vial, the use of large amounts of99mTc activity (i.e., 3.7 GBq) or the reconstitution of large volumes. The use of this radiopharmaceutical in mice showed a minimal accumulation in the hepatobiliary system (0.37±0.3% I.D., 1 h postinjection). However, in rabbits we always obtained good image quality.
package_name Springer
publikationsjahr_anzeige 1995
publikationsjahr_facette 1995
publikationsjahr_intervall 8004:1995-1999
publikationsjahr_sort 1995
publisher Springer
reference 199 (1995), S. 507-516
search_space articles
shingle_author_1 Reyes-Herrera, L.
Ferro-Flores, G.
Lezama-Carrasco, J.
Gonzalez-Zavala, M. A.
Ureña-Nuñez, F.
Avila-Ramirez, E.
shingle_author_2 Reyes-Herrera, L.
Ferro-Flores, G.
Lezama-Carrasco, J.
Gonzalez-Zavala, M. A.
Ureña-Nuñez, F.
Avila-Ramirez, E.
shingle_author_3 Reyes-Herrera, L.
Ferro-Flores, G.
Lezama-Carrasco, J.
Gonzalez-Zavala, M. A.
Ureña-Nuñez, F.
Avila-Ramirez, E.
shingle_author_4 Reyes-Herrera, L.
Ferro-Flores, G.
Lezama-Carrasco, J.
Gonzalez-Zavala, M. A.
Ureña-Nuñez, F.
Avila-Ramirez, E.
shingle_catch_all_1 Reyes-Herrera, L.
Ferro-Flores, G.
Lezama-Carrasco, J.
Gonzalez-Zavala, M. A.
Ureña-Nuñez, F.
Avila-Ramirez, E.
An alkaline kit formulation to obtain [99mTc]MAG3 in high radiochemical yields
Abstract An alkaline kit formulation (pH 9) to obtain [99mTc]MAG3 with radiochemical puritives over 98% has been developed, avoiding the addition of filtered air to the vial, the use of large amounts of99mTc activity (i.e., 3.7 GBq) or the reconstitution of large volumes. The use of this radiopharmaceutical in mice showed a minimal accumulation in the hepatobiliary system (0.37±0.3% I.D., 1 h postinjection). However, in rabbits we always obtained good image quality.
1588-2780
15882780
Springer
shingle_catch_all_2 Reyes-Herrera, L.
Ferro-Flores, G.
Lezama-Carrasco, J.
Gonzalez-Zavala, M. A.
Ureña-Nuñez, F.
Avila-Ramirez, E.
An alkaline kit formulation to obtain [99mTc]MAG3 in high radiochemical yields
Abstract An alkaline kit formulation (pH 9) to obtain [99mTc]MAG3 with radiochemical puritives over 98% has been developed, avoiding the addition of filtered air to the vial, the use of large amounts of99mTc activity (i.e., 3.7 GBq) or the reconstitution of large volumes. The use of this radiopharmaceutical in mice showed a minimal accumulation in the hepatobiliary system (0.37±0.3% I.D., 1 h postinjection). However, in rabbits we always obtained good image quality.
1588-2780
15882780
Springer
shingle_catch_all_3 Reyes-Herrera, L.
Ferro-Flores, G.
Lezama-Carrasco, J.
Gonzalez-Zavala, M. A.
Ureña-Nuñez, F.
Avila-Ramirez, E.
An alkaline kit formulation to obtain [99mTc]MAG3 in high radiochemical yields
Abstract An alkaline kit formulation (pH 9) to obtain [99mTc]MAG3 with radiochemical puritives over 98% has been developed, avoiding the addition of filtered air to the vial, the use of large amounts of99mTc activity (i.e., 3.7 GBq) or the reconstitution of large volumes. The use of this radiopharmaceutical in mice showed a minimal accumulation in the hepatobiliary system (0.37±0.3% I.D., 1 h postinjection). However, in rabbits we always obtained good image quality.
1588-2780
15882780
Springer
shingle_catch_all_4 Reyes-Herrera, L.
Ferro-Flores, G.
Lezama-Carrasco, J.
Gonzalez-Zavala, M. A.
Ureña-Nuñez, F.
Avila-Ramirez, E.
An alkaline kit formulation to obtain [99mTc]MAG3 in high radiochemical yields
Abstract An alkaline kit formulation (pH 9) to obtain [99mTc]MAG3 with radiochemical puritives over 98% has been developed, avoiding the addition of filtered air to the vial, the use of large amounts of99mTc activity (i.e., 3.7 GBq) or the reconstitution of large volumes. The use of this radiopharmaceutical in mice showed a minimal accumulation in the hepatobiliary system (0.37±0.3% I.D., 1 h postinjection). However, in rabbits we always obtained good image quality.
1588-2780
15882780
Springer
shingle_title_1 An alkaline kit formulation to obtain [99mTc]MAG3 in high radiochemical yields
shingle_title_2 An alkaline kit formulation to obtain [99mTc]MAG3 in high radiochemical yields
shingle_title_3 An alkaline kit formulation to obtain [99mTc]MAG3 in high radiochemical yields
shingle_title_4 An alkaline kit formulation to obtain [99mTc]MAG3 in high radiochemical yields
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source_archive Springer Online Journal Archives 1860-2000
timestamp 2024-05-06T10:05:45.636Z
titel An alkaline kit formulation to obtain [99mTc]MAG3 in high radiochemical yields
titel_suche An alkaline kit formulation to obtain [99mTc]MAG3 in high radiochemical yields
topic V
ZP
uid nat_lic_papers_NLM194927059