An alkaline kit formulation to obtain [99mTc]MAG3 in high radiochemical yields
Reyes-Herrera, L. ; Ferro-Flores, G. ; Lezama-Carrasco, J. ; Gonzalez-Zavala, M. A. ; Ureña-Nuñez, F. ; Avila-Ramirez, E.
Springer
Published 1995
Springer
Published 1995
| ISSN: |
1588-2780
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|---|---|
| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Chemistry and Pharmacology
Energy, Environment Protection, Nuclear Power Engineering
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| Notes: |
Abstract An alkaline kit formulation (pH 9) to obtain [99mTc]MAG3 with radiochemical puritives over 98% has been developed, avoiding the addition of filtered air to the vial, the use of large amounts of99mTc activity (i.e., 3.7 GBq) or the reconstitution of large volumes. The use of this radiopharmaceutical in mice showed a minimal accumulation in the hepatobiliary system (0.37±0.3% I.D., 1 h postinjection). However, in rabbits we always obtained good image quality.
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| Type of Medium: |
Electronic Resource
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| URL: |