Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection

ISSN:
1573-2630
Keywords:
aqueous ; cyclosporine ; HPLC ; liposome ; rabbit ; vitreous
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups.
Type of Medium:
Electronic Resource
URL:
_version_ 1798296654107901952
autor Alghadyan, Abdulrahman A.
Peyman, Gholam A.
Khoobehi, Bahram
Milner, Steve
Liu, K. R.
autorsonst Alghadyan, Abdulrahman A.
Peyman, Gholam A.
Khoobehi, Bahram
Milner, Steve
Liu, K. R.
book_url http://dx.doi.org/10.1007/BF00137133
datenlieferant nat_lic_papers
hauptsatz hsatz_simple
identnr NLM194441075
issn 1573-2630
journal_name International ophthalmology
materialart 1
notes Abstract The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups.
package_name Springer
publikationsjahr_anzeige 1988
publikationsjahr_facette 1988
publikationsjahr_intervall 8014:1985-1989
publikationsjahr_sort 1988
publisher Springer
reference 12 (1988), S. 101-104
schlagwort aqueous
cyclosporine
HPLC
liposome
rabbit
vitreous
search_space articles
shingle_author_1 Alghadyan, Abdulrahman A.
Peyman, Gholam A.
Khoobehi, Bahram
Milner, Steve
Liu, K. R.
shingle_author_2 Alghadyan, Abdulrahman A.
Peyman, Gholam A.
Khoobehi, Bahram
Milner, Steve
Liu, K. R.
shingle_author_3 Alghadyan, Abdulrahman A.
Peyman, Gholam A.
Khoobehi, Bahram
Milner, Steve
Liu, K. R.
shingle_author_4 Alghadyan, Abdulrahman A.
Peyman, Gholam A.
Khoobehi, Bahram
Milner, Steve
Liu, K. R.
shingle_catch_all_1 Alghadyan, Abdulrahman A.
Peyman, Gholam A.
Khoobehi, Bahram
Milner, Steve
Liu, K. R.
Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection
aqueous
cyclosporine
HPLC
liposome
rabbit
vitreous
aqueous
cyclosporine
HPLC
liposome
rabbit
vitreous
Abstract The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups.
1573-2630
15732630
Springer
shingle_catch_all_2 Alghadyan, Abdulrahman A.
Peyman, Gholam A.
Khoobehi, Bahram
Milner, Steve
Liu, K. R.
Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection
aqueous
cyclosporine
HPLC
liposome
rabbit
vitreous
aqueous
cyclosporine
HPLC
liposome
rabbit
vitreous
Abstract The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups.
1573-2630
15732630
Springer
shingle_catch_all_3 Alghadyan, Abdulrahman A.
Peyman, Gholam A.
Khoobehi, Bahram
Milner, Steve
Liu, K. R.
Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection
aqueous
cyclosporine
HPLC
liposome
rabbit
vitreous
aqueous
cyclosporine
HPLC
liposome
rabbit
vitreous
Abstract The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups.
1573-2630
15732630
Springer
shingle_catch_all_4 Alghadyan, Abdulrahman A.
Peyman, Gholam A.
Khoobehi, Bahram
Milner, Steve
Liu, K. R.
Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection
aqueous
cyclosporine
HPLC
liposome
rabbit
vitreous
aqueous
cyclosporine
HPLC
liposome
rabbit
vitreous
Abstract The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups.
1573-2630
15732630
Springer
shingle_title_1 Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection
shingle_title_2 Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection
shingle_title_3 Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection
shingle_title_4 Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection
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source_archive Springer Online Journal Archives 1860-2000
timestamp 2024-05-06T09:55:31.733Z
titel Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection
titel_suche Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection
topic WW-YZ
uid nat_lic_papers_NLM194441075