Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection
Alghadyan, Abdulrahman A. ; Peyman, Gholam A. ; Khoobehi, Bahram ; Milner, Steve ; Liu, K. R.
Springer
Published 1988
Springer
Published 1988
ISSN: |
1573-2630
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Keywords: |
aqueous ; cyclosporine ; HPLC ; liposome ; rabbit ; vitreous
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Source: |
Springer Online Journal Archives 1860-2000
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Topics: |
Medicine
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Notes: |
Abstract The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups.
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Type of Medium: |
Electronic Resource
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URL: |
_version_ | 1798296654107901952 |
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autor | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, K. R. |
autorsonst | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, K. R. |
book_url | http://dx.doi.org/10.1007/BF00137133 |
datenlieferant | nat_lic_papers |
hauptsatz | hsatz_simple |
identnr | NLM194441075 |
issn | 1573-2630 |
journal_name | International ophthalmology |
materialart | 1 |
notes | Abstract The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups. |
package_name | Springer |
publikationsjahr_anzeige | 1988 |
publikationsjahr_facette | 1988 |
publikationsjahr_intervall | 8014:1985-1989 |
publikationsjahr_sort | 1988 |
publisher | Springer |
reference | 12 (1988), S. 101-104 |
schlagwort | aqueous cyclosporine HPLC liposome rabbit vitreous |
search_space | articles |
shingle_author_1 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, K. R. |
shingle_author_2 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, K. R. |
shingle_author_3 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, K. R. |
shingle_author_4 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, K. R. |
shingle_catch_all_1 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, K. R. Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection aqueous cyclosporine HPLC liposome rabbit vitreous aqueous cyclosporine HPLC liposome rabbit vitreous Abstract The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups. 1573-2630 15732630 Springer |
shingle_catch_all_2 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, K. R. Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection aqueous cyclosporine HPLC liposome rabbit vitreous aqueous cyclosporine HPLC liposome rabbit vitreous Abstract The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups. 1573-2630 15732630 Springer |
shingle_catch_all_3 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, K. R. Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection aqueous cyclosporine HPLC liposome rabbit vitreous aqueous cyclosporine HPLC liposome rabbit vitreous Abstract The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups. 1573-2630 15732630 Springer |
shingle_catch_all_4 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, K. R. Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection aqueous cyclosporine HPLC liposome rabbit vitreous aqueous cyclosporine HPLC liposome rabbit vitreous Abstract The concentration of cyclosporine in the aqueous and vitreous humors of albino rabbits was measured, using HPLC at intervals of 24, 48, 96, and 192 hours after subconjunctival injections of 2.5 mg of free or liposome-bound cyclosporine. The aqueous concentration was reasonably high in both groups until day 4: 1050 nanograms per milliliter in the group receiving free cyclosporine, and 1438 nanograms per milliliter in the group receiving liposome-bound cyclosporine. The vitreous concentration was very low in both groups. 1573-2630 15732630 Springer |
shingle_title_1 | Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection |
shingle_title_2 | Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection |
shingle_title_3 | Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection |
shingle_title_4 | Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection |
sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
source_archive | Springer Online Journal Archives 1860-2000 |
timestamp | 2024-05-06T09:55:31.733Z |
titel | Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection |
titel_suche | Liposome-bound cyclosporine: Aqueous and vitreous level after subconjunctival injection |
topic | WW-YZ |
uid | nat_lic_papers_NLM194441075 |