Properties of Liposomes Prepared with Various Lipids
Hsieh, Y.-F. ; Chen, T.-L. ; Wang, Y.-T. ; Chang, J.-H. ; Chang, H.-M.
Oxford, UK : Blackwell Publishing Ltd
Published 2002
Oxford, UK : Blackwell Publishing Ltd
Published 2002
ISSN: |
1750-3841
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Source: |
Blackwell Publishing Journal Backfiles 1879-2005
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Topics: |
Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
Process Engineering, Biotechnology, Nutrition Technology
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Notes: |
: Use of several lipids as an alternative to cholesterol to prepare stable liposomes was tried. Liposome prepared at 1/0.25 lecithin/stearic acid ratio exhibited better (55%) encapsulation efficiency (EE) of bovine serum albumin (BSA) than that (41%) prepared at 1/0.25 lecithin/cholesterol ratio. Liposomes showed the minimal released percentage of encapsulated BSA at pH 6. Storage at −20 °C caused serious damage to liposomes. Addition of α–tocopherol was effective in stabilizing liposomes. Liposomes, incorporated with α–amylase, prepared at 1/0.25 lecithin/cholesterol or stearic acid ratio were effective in protecting enzyme against acid (pH 2.8) and pepsin (15 mg/mL). Use of stearic acid, instead of cholesterol, would be feasible in preparing stable liposomes.
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Type of Medium: |
Electronic Resource
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URL: |
_version_ | 1798290358959865857 |
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autor | Hsieh, Y.-F. Chen, T.-L. Wang, Y.-T. Chang, J.-H. Chang, H.-M. |
autorsonst | Chang, J.-H. Chang, H.-M. |
book_url | http://dx.doi.org/10.1111/j.1365-2621.2002.tb08820.x |
datenlieferant | nat_lic_papers |
hauptsatz | hsatz_simple |
identnr | NLZ243212356 |
insertion_date | 2012-04-27 |
issn | 1750-3841 |
journal_name | Journal of food science |
materialart | 1 |
notes | : Use of several lipids as an alternative to cholesterol to prepare stable liposomes was tried. Liposome prepared at 1/0.25 lecithin/stearic acid ratio exhibited better (55%) encapsulation efficiency (EE) of bovine serum albumin (BSA) than that (41%) prepared at 1/0.25 lecithin/cholesterol ratio. Liposomes showed the minimal released percentage of encapsulated BSA at pH 6. Storage at −20 °C caused serious damage to liposomes. Addition of α–tocopherol was effective in stabilizing liposomes. Liposomes, incorporated with α–amylase, prepared at 1/0.25 lecithin/cholesterol or stearic acid ratio were effective in protecting enzyme against acid (pH 2.8) and pepsin (15 mg/mL). Use of stearic acid, instead of cholesterol, would be feasible in preparing stable liposomes. |
package_name | Blackwell Publishing |
publikationsjahr_anzeige | 2002 |
publikationsjahr_facette | 2002 |
publikationsjahr_intervall | 7999:2000-2004 |
publikationsjahr_sort | 2002 |
publikationsort | Oxford, UK |
publisher | Blackwell Publishing Ltd |
reference | 67 (2002), S. 0 |
search_space | articles |
shingle_author_1 | Hsieh, Y.-F. Chen, T.-L. Wang, Y.-T. Chang, J.-H. Chang, H.-M. |
shingle_author_2 | Hsieh, Y.-F. Chen, T.-L. Wang, Y.-T. Chang, J.-H. Chang, H.-M. |
shingle_author_3 | Hsieh, Y.-F. Chen, T.-L. Wang, Y.-T. Chang, J.-H. Chang, H.-M. |
shingle_author_4 | Hsieh, Y.-F. Chen, T.-L. Wang, Y.-T. Chang, J.-H. Chang, H.-M. |
shingle_catch_all_1 | Hsieh, Y.-F. Chen, T.-L. Wang, Y.-T. Chang, J.-H. Chang, H.-M. Properties of Liposomes Prepared with Various Lipids Blackwell Publishing Ltd : Use of several lipids as an alternative to cholesterol to prepare stable liposomes was tried. Liposome prepared at 1/0.25 lecithin/stearic acid ratio exhibited better (55%) encapsulation efficiency (EE) of bovine serum albumin (BSA) than that (41%) prepared at 1/0.25 lecithin/cholesterol ratio. Liposomes showed the minimal released percentage of encapsulated BSA at pH 6. Storage at −20 °C caused serious damage to liposomes. Addition of α–tocopherol was effective in stabilizing liposomes. Liposomes, incorporated with α–amylase, prepared at 1/0.25 lecithin/cholesterol or stearic acid ratio were effective in protecting enzyme against acid (pH 2.8) and pepsin (15 mg/mL). Use of stearic acid, instead of cholesterol, would be feasible in preparing stable liposomes. 1750-3841 17503841 |
shingle_catch_all_2 | Hsieh, Y.-F. Chen, T.-L. Wang, Y.-T. Chang, J.-H. Chang, H.-M. Properties of Liposomes Prepared with Various Lipids Blackwell Publishing Ltd : Use of several lipids as an alternative to cholesterol to prepare stable liposomes was tried. Liposome prepared at 1/0.25 lecithin/stearic acid ratio exhibited better (55%) encapsulation efficiency (EE) of bovine serum albumin (BSA) than that (41%) prepared at 1/0.25 lecithin/cholesterol ratio. Liposomes showed the minimal released percentage of encapsulated BSA at pH 6. Storage at −20 °C caused serious damage to liposomes. Addition of α–tocopherol was effective in stabilizing liposomes. Liposomes, incorporated with α–amylase, prepared at 1/0.25 lecithin/cholesterol or stearic acid ratio were effective in protecting enzyme against acid (pH 2.8) and pepsin (15 mg/mL). Use of stearic acid, instead of cholesterol, would be feasible in preparing stable liposomes. 1750-3841 17503841 |
shingle_catch_all_3 | Hsieh, Y.-F. Chen, T.-L. Wang, Y.-T. Chang, J.-H. Chang, H.-M. Properties of Liposomes Prepared with Various Lipids Blackwell Publishing Ltd : Use of several lipids as an alternative to cholesterol to prepare stable liposomes was tried. Liposome prepared at 1/0.25 lecithin/stearic acid ratio exhibited better (55%) encapsulation efficiency (EE) of bovine serum albumin (BSA) than that (41%) prepared at 1/0.25 lecithin/cholesterol ratio. Liposomes showed the minimal released percentage of encapsulated BSA at pH 6. Storage at −20 °C caused serious damage to liposomes. Addition of α–tocopherol was effective in stabilizing liposomes. Liposomes, incorporated with α–amylase, prepared at 1/0.25 lecithin/cholesterol or stearic acid ratio were effective in protecting enzyme against acid (pH 2.8) and pepsin (15 mg/mL). Use of stearic acid, instead of cholesterol, would be feasible in preparing stable liposomes. 1750-3841 17503841 |
shingle_catch_all_4 | Hsieh, Y.-F. Chen, T.-L. Wang, Y.-T. Chang, J.-H. Chang, H.-M. Properties of Liposomes Prepared with Various Lipids Blackwell Publishing Ltd : Use of several lipids as an alternative to cholesterol to prepare stable liposomes was tried. Liposome prepared at 1/0.25 lecithin/stearic acid ratio exhibited better (55%) encapsulation efficiency (EE) of bovine serum albumin (BSA) than that (41%) prepared at 1/0.25 lecithin/cholesterol ratio. Liposomes showed the minimal released percentage of encapsulated BSA at pH 6. Storage at −20 °C caused serious damage to liposomes. Addition of α–tocopherol was effective in stabilizing liposomes. Liposomes, incorporated with α–amylase, prepared at 1/0.25 lecithin/cholesterol or stearic acid ratio were effective in protecting enzyme against acid (pH 2.8) and pepsin (15 mg/mL). Use of stearic acid, instead of cholesterol, would be feasible in preparing stable liposomes. 1750-3841 17503841 |
shingle_title_1 | Properties of Liposomes Prepared with Various Lipids |
shingle_title_2 | Properties of Liposomes Prepared with Various Lipids |
shingle_title_3 | Properties of Liposomes Prepared with Various Lipids |
shingle_title_4 | Properties of Liposomes Prepared with Various Lipids |
sigel_instance_filter | dkfz geomar wilbert ipn albert |
source_archive | Blackwell Publishing Journal Backfiles 1879-2005 |
timestamp | 2024-05-06T08:15:28.690Z |
titel | Properties of Liposomes Prepared with Various Lipids |
titel_suche | Properties of Liposomes Prepared with Various Lipids |
topic | ZA-ZE ZM |
uid | nat_lic_papers_NLZ243212356 |