Synaptic Vesicle Ultrastructural Changes in the Rat Hippocampus Induced by a Combination of α-Linolenate Deficiency and a Learning Task
Yoshida, S. ; Yasuda, A. ; Kawazato, H. ; Sakai, K. ; Shimada, T. ; Takeshita, M. ; Yuasa, S. ; Kobayashi, T. ; Watanabe, S. ; Okuyama, H.
Oxford, UK : Blackwell Science Ltd
Published 1997
Oxford, UK : Blackwell Science Ltd
Published 1997
| ISSN: |
1471-4159
|
|---|---|
| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
|
| Topics: |
Medicine
|
| Notes: |
Abstract: Rats fed either a safflower oil (α-linolenate-deficient) or a perilla oil (α-linolenate-sufficient) diet through two generations (F1) showed significant differences in the brightness-discrimination learning task. In this task, correct responses were lever-pressing responses, which were reinforced with dietary pellets, and incorrect responses were those with no reinforcement. The inferior learning performance in the safflower oil group was caused mainly by the inferior ability to rectify the incorrect responses through the learning sessions. In the safflower oil group after the learning task, the average densities of synaptic vesicles in the terminals of the hippocampus CA1 region were decreased by nearly 30% as compared with those in the perilla oil group, and it is notable that this difference was not detected without the learning task. These results suggest that dietary oil-induced morphological changes in synapses in the hippocampus of rats are related to the differential learning performance and that the turnover rate of synaptic vesicles in the hippocampus may be an important factor affecting learning performance.
|
| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798290009327927296 |
|---|---|
| autor | Yoshida, S. Yasuda, A. Kawazato, H. Sakai, K. Shimada, T. Takeshita, M. Yuasa, S. Kobayashi, T. Watanabe, S. Okuyama, H. |
| autorsonst | Yoshida, S. Yasuda, A. Kawazato, H. Sakai, K. Shimada, T. Takeshita, M. Yuasa, S. Kobayashi, T. Watanabe, S. Okuyama, H. |
| book_url | http://dx.doi.org/10.1046/j.1471-4159.1997.68031261.x |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLZ243169833 |
| insertion_date | 2012-04-27 |
| issn | 1471-4159 |
| journal_name | Journal of neurochemistry |
| materialart | 1 |
| notes | Abstract: Rats fed either a safflower oil (α-linolenate-deficient) or a perilla oil (α-linolenate-sufficient) diet through two generations (F1) showed significant differences in the brightness-discrimination learning task. In this task, correct responses were lever-pressing responses, which were reinforced with dietary pellets, and incorrect responses were those with no reinforcement. The inferior learning performance in the safflower oil group was caused mainly by the inferior ability to rectify the incorrect responses through the learning sessions. In the safflower oil group after the learning task, the average densities of synaptic vesicles in the terminals of the hippocampus CA1 region were decreased by nearly 30% as compared with those in the perilla oil group, and it is notable that this difference was not detected without the learning task. These results suggest that dietary oil-induced morphological changes in synapses in the hippocampus of rats are related to the differential learning performance and that the turnover rate of synaptic vesicles in the hippocampus may be an important factor affecting learning performance. |
| package_name | Blackwell Publishing |
| publikationsjahr_anzeige | 1997 |
| publikationsjahr_facette | 1997 |
| publikationsjahr_intervall | 8004:1995-1999 |
| publikationsjahr_sort | 1997 |
| publikationsort | Oxford, UK |
| publisher | Blackwell Science Ltd |
| reference | 68 (1997), S. 0 |
| search_space | articles |
| shingle_author_1 | Yoshida, S. Yasuda, A. Kawazato, H. Sakai, K. Shimada, T. Takeshita, M. Yuasa, S. Kobayashi, T. Watanabe, S. Okuyama, H. |
| shingle_author_2 | Yoshida, S. Yasuda, A. Kawazato, H. Sakai, K. Shimada, T. Takeshita, M. Yuasa, S. Kobayashi, T. Watanabe, S. Okuyama, H. |
| shingle_author_3 | Yoshida, S. Yasuda, A. Kawazato, H. Sakai, K. Shimada, T. Takeshita, M. Yuasa, S. Kobayashi, T. Watanabe, S. Okuyama, H. |
| shingle_author_4 | Yoshida, S. Yasuda, A. Kawazato, H. Sakai, K. Shimada, T. Takeshita, M. Yuasa, S. Kobayashi, T. Watanabe, S. Okuyama, H. |
| shingle_catch_all_1 | Yoshida, S. Yasuda, A. Kawazato, H. Sakai, K. Shimada, T. Takeshita, M. Yuasa, S. Kobayashi, T. Watanabe, S. Okuyama, H. Synaptic Vesicle Ultrastructural Changes in the Rat Hippocampus Induced by a Combination of α-Linolenate Deficiency and a Learning Task Blackwell Science Ltd Abstract: Rats fed either a safflower oil (α-linolenate-deficient) or a perilla oil (α-linolenate-sufficient) diet through two generations (F1) showed significant differences in the brightness-discrimination learning task. In this task, correct responses were lever-pressing responses, which were reinforced with dietary pellets, and incorrect responses were those with no reinforcement. The inferior learning performance in the safflower oil group was caused mainly by the inferior ability to rectify the incorrect responses through the learning sessions. In the safflower oil group after the learning task, the average densities of synaptic vesicles in the terminals of the hippocampus CA1 region were decreased by nearly 30% as compared with those in the perilla oil group, and it is notable that this difference was not detected without the learning task. These results suggest that dietary oil-induced morphological changes in synapses in the hippocampus of rats are related to the differential learning performance and that the turnover rate of synaptic vesicles in the hippocampus may be an important factor affecting learning performance. 1471-4159 14714159 |
| shingle_catch_all_2 | Yoshida, S. Yasuda, A. Kawazato, H. Sakai, K. Shimada, T. Takeshita, M. Yuasa, S. Kobayashi, T. Watanabe, S. Okuyama, H. Synaptic Vesicle Ultrastructural Changes in the Rat Hippocampus Induced by a Combination of α-Linolenate Deficiency and a Learning Task Blackwell Science Ltd Abstract: Rats fed either a safflower oil (α-linolenate-deficient) or a perilla oil (α-linolenate-sufficient) diet through two generations (F1) showed significant differences in the brightness-discrimination learning task. In this task, correct responses were lever-pressing responses, which were reinforced with dietary pellets, and incorrect responses were those with no reinforcement. The inferior learning performance in the safflower oil group was caused mainly by the inferior ability to rectify the incorrect responses through the learning sessions. In the safflower oil group after the learning task, the average densities of synaptic vesicles in the terminals of the hippocampus CA1 region were decreased by nearly 30% as compared with those in the perilla oil group, and it is notable that this difference was not detected without the learning task. These results suggest that dietary oil-induced morphological changes in synapses in the hippocampus of rats are related to the differential learning performance and that the turnover rate of synaptic vesicles in the hippocampus may be an important factor affecting learning performance. 1471-4159 14714159 |
| shingle_catch_all_3 | Yoshida, S. Yasuda, A. Kawazato, H. Sakai, K. Shimada, T. Takeshita, M. Yuasa, S. Kobayashi, T. Watanabe, S. Okuyama, H. Synaptic Vesicle Ultrastructural Changes in the Rat Hippocampus Induced by a Combination of α-Linolenate Deficiency and a Learning Task Blackwell Science Ltd Abstract: Rats fed either a safflower oil (α-linolenate-deficient) or a perilla oil (α-linolenate-sufficient) diet through two generations (F1) showed significant differences in the brightness-discrimination learning task. In this task, correct responses were lever-pressing responses, which were reinforced with dietary pellets, and incorrect responses were those with no reinforcement. The inferior learning performance in the safflower oil group was caused mainly by the inferior ability to rectify the incorrect responses through the learning sessions. In the safflower oil group after the learning task, the average densities of synaptic vesicles in the terminals of the hippocampus CA1 region were decreased by nearly 30% as compared with those in the perilla oil group, and it is notable that this difference was not detected without the learning task. These results suggest that dietary oil-induced morphological changes in synapses in the hippocampus of rats are related to the differential learning performance and that the turnover rate of synaptic vesicles in the hippocampus may be an important factor affecting learning performance. 1471-4159 14714159 |
| shingle_catch_all_4 | Yoshida, S. Yasuda, A. Kawazato, H. Sakai, K. Shimada, T. Takeshita, M. Yuasa, S. Kobayashi, T. Watanabe, S. Okuyama, H. Synaptic Vesicle Ultrastructural Changes in the Rat Hippocampus Induced by a Combination of α-Linolenate Deficiency and a Learning Task Blackwell Science Ltd Abstract: Rats fed either a safflower oil (α-linolenate-deficient) or a perilla oil (α-linolenate-sufficient) diet through two generations (F1) showed significant differences in the brightness-discrimination learning task. In this task, correct responses were lever-pressing responses, which were reinforced with dietary pellets, and incorrect responses were those with no reinforcement. The inferior learning performance in the safflower oil group was caused mainly by the inferior ability to rectify the incorrect responses through the learning sessions. In the safflower oil group after the learning task, the average densities of synaptic vesicles in the terminals of the hippocampus CA1 region were decreased by nearly 30% as compared with those in the perilla oil group, and it is notable that this difference was not detected without the learning task. These results suggest that dietary oil-induced morphological changes in synapses in the hippocampus of rats are related to the differential learning performance and that the turnover rate of synaptic vesicles in the hippocampus may be an important factor affecting learning performance. 1471-4159 14714159 |
| shingle_title_1 | Synaptic Vesicle Ultrastructural Changes in the Rat Hippocampus Induced by a Combination of α-Linolenate Deficiency and a Learning Task |
| shingle_title_2 | Synaptic Vesicle Ultrastructural Changes in the Rat Hippocampus Induced by a Combination of α-Linolenate Deficiency and a Learning Task |
| shingle_title_3 | Synaptic Vesicle Ultrastructural Changes in the Rat Hippocampus Induced by a Combination of α-Linolenate Deficiency and a Learning Task |
| shingle_title_4 | Synaptic Vesicle Ultrastructural Changes in the Rat Hippocampus Induced by a Combination of α-Linolenate Deficiency and a Learning Task |
| sigel_instance_filter | dkfz geomar wilbert ipn albert |
| source_archive | Blackwell Publishing Journal Backfiles 1879-2005 |
| timestamp | 2024-05-06T08:09:53.760Z |
| titel | Synaptic Vesicle Ultrastructural Changes in the Rat Hippocampus Induced by a Combination of α-Linolenate Deficiency and a Learning Task |
| titel_suche | Synaptic Vesicle Ultrastructural Changes in the Rat Hippocampus Induced by a Combination of α-Linolenate Deficiency and a Learning Task |
| topic | WW-YZ |
| uid | nat_lic_papers_NLZ243169833 |