Squamoid eccrine ductal carcinoma

WONG, T-Y. ; SUSTER, S. ; MIHM, M.C.

Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
Published 1997
ISSN:
1365-2559
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
We describe three cases of a distinctive cutaneous adnexal neoplasm showing features of eccrine ductal differentiation that were characterized by a prominent squamoid component. The tumours presented as solitary dermal nodules on the head and neck areas and the extremities in elderly patients. Histologically, they were characterized by a prominent squamous proliferation with atypia, keratinous cyst formation and squamous eddies which seemed to merge with areas showing eccrine ductal differentiation, including ductular formations in continuity with eccrine ductal epithelium. Clinical follow-up in one case showed multiple local recurrences over a period of 3 years despite complete surgical excision. Squamoid eccrine ductal carcinoma should be considered in the differential diagnosis of cutaneous adnexal neoplasms showing squamoid and ductal features of differentiation.
Type of Medium:
Electronic Resource
URL: