Post-transplant lymphoproliferative disorder limited to the skin

Samolitis, Nancy J. ; Bharadwaj, Jayaram S. ; Weis, John R. ; Harris, Ronald M.

Oxford, UK; Malden, USA : Munksgaard International Publishers
Published 2004
ISSN:
1600-0560
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Background:  Post-transplant lymphoproliferative disorder (PTLD) is a condition affecting immunosuppressed transplant patients and has a variety of clinical presentations. It is rarely found in the skin, and cases of PTLD in the skin are usually linked with lymph node or other organ involvement.Methods:  We report a case of plasmacytoid PTLD that is limited to the skin. A 63-year-old man with a history of cardiac transplant presented with exophytic tumors involving the lower extremity. The diagnosis and classification of the various forms of PTLD are discussed.Results:  Histology, immunohistochemical stains, and in situ hybridization revealed an aggressive plasmacytoid tumor that was Epstein–Barr virus positive. The patient's tumors resolved with decreased immunosuppression and localized radiation.Conclusion:  This case is unusual for several reasons including involvement limited to the skin, presentation 15 years following transplant, and plasmacytoid phenotype of the tumor. This disorder will likely be seen by dermatologists and dermatopathologists with the increasing use of immunosuppressive medications in the dermatologist's patient population.
Type of Medium:
Electronic Resource
URL:
_version_ 1798290487341219840
autor Samolitis, Nancy J.
Bharadwaj, Jayaram S.
Weis, John R.
Harris, Ronald M.
autorsonst Harris, Ronald M.
book_url http://dx.doi.org/10.1111/j.0303-6987.2004.00197.x
datenlieferant nat_lic_papers
hauptsatz hsatz_simple
identnr NLZ242494218
insertion_date 2012-04-27
issn 1600-0560
journal_name Journal of cutaneous pathology
materialart 1
notes Background:  Post-transplant lymphoproliferative disorder (PTLD) is a condition affecting immunosuppressed transplant patients and has a variety of clinical presentations. It is rarely found in the skin, and cases of PTLD in the skin are usually linked with lymph node or other organ involvement.Methods:  We report a case of plasmacytoid PTLD that is limited to the skin. A 63-year-old man with a history of cardiac transplant presented with exophytic tumors involving the lower extremity. The diagnosis and classification of the various forms of PTLD are discussed.Results:  Histology, immunohistochemical stains, and in situ hybridization revealed an aggressive plasmacytoid tumor that was Epstein–Barr virus positive. The patient's tumors resolved with decreased immunosuppression and localized radiation.Conclusion:  This case is unusual for several reasons including involvement limited to the skin, presentation 15 years following transplant, and plasmacytoid phenotype of the tumor. This disorder will likely be seen by dermatologists and dermatopathologists with the increasing use of immunosuppressive medications in the dermatologist's patient population.
package_name Blackwell Publishing
publikationsjahr_anzeige 2004
publikationsjahr_facette 2004
publikationsjahr_intervall 7999:2000-2004
publikationsjahr_sort 2004
publikationsort Oxford, UK; Malden, USA
publisher Munksgaard International Publishers
reference 31 (2004), S. 0
search_space articles
shingle_author_1 Samolitis, Nancy J.
Bharadwaj, Jayaram S.
Weis, John R.
Harris, Ronald M.
shingle_author_2 Samolitis, Nancy J.
Bharadwaj, Jayaram S.
Weis, John R.
Harris, Ronald M.
shingle_author_3 Samolitis, Nancy J.
Bharadwaj, Jayaram S.
Weis, John R.
Harris, Ronald M.
shingle_author_4 Samolitis, Nancy J.
Bharadwaj, Jayaram S.
Weis, John R.
Harris, Ronald M.
shingle_catch_all_1 Samolitis, Nancy J.
Bharadwaj, Jayaram S.
Weis, John R.
Harris, Ronald M.
Post-transplant lymphoproliferative disorder limited to the skin
Munksgaard International Publishers
Background:  Post-transplant lymphoproliferative disorder (PTLD) is a condition affecting immunosuppressed transplant patients and has a variety of clinical presentations. It is rarely found in the skin, and cases of PTLD in the skin are usually linked with lymph node or other organ involvement.Methods:  We report a case of plasmacytoid PTLD that is limited to the skin. A 63-year-old man with a history of cardiac transplant presented with exophytic tumors involving the lower extremity. The diagnosis and classification of the various forms of PTLD are discussed.Results:  Histology, immunohistochemical stains, and in situ hybridization revealed an aggressive plasmacytoid tumor that was Epstein–Barr virus positive. The patient's tumors resolved with decreased immunosuppression and localized radiation.Conclusion:  This case is unusual for several reasons including involvement limited to the skin, presentation 15 years following transplant, and plasmacytoid phenotype of the tumor. This disorder will likely be seen by dermatologists and dermatopathologists with the increasing use of immunosuppressive medications in the dermatologist's patient population.
1600-0560
16000560
shingle_catch_all_2 Samolitis, Nancy J.
Bharadwaj, Jayaram S.
Weis, John R.
Harris, Ronald M.
Post-transplant lymphoproliferative disorder limited to the skin
Munksgaard International Publishers
Background:  Post-transplant lymphoproliferative disorder (PTLD) is a condition affecting immunosuppressed transplant patients and has a variety of clinical presentations. It is rarely found in the skin, and cases of PTLD in the skin are usually linked with lymph node or other organ involvement.Methods:  We report a case of plasmacytoid PTLD that is limited to the skin. A 63-year-old man with a history of cardiac transplant presented with exophytic tumors involving the lower extremity. The diagnosis and classification of the various forms of PTLD are discussed.Results:  Histology, immunohistochemical stains, and in situ hybridization revealed an aggressive plasmacytoid tumor that was Epstein–Barr virus positive. The patient's tumors resolved with decreased immunosuppression and localized radiation.Conclusion:  This case is unusual for several reasons including involvement limited to the skin, presentation 15 years following transplant, and plasmacytoid phenotype of the tumor. This disorder will likely be seen by dermatologists and dermatopathologists with the increasing use of immunosuppressive medications in the dermatologist's patient population.
1600-0560
16000560
shingle_catch_all_3 Samolitis, Nancy J.
Bharadwaj, Jayaram S.
Weis, John R.
Harris, Ronald M.
Post-transplant lymphoproliferative disorder limited to the skin
Munksgaard International Publishers
Background:  Post-transplant lymphoproliferative disorder (PTLD) is a condition affecting immunosuppressed transplant patients and has a variety of clinical presentations. It is rarely found in the skin, and cases of PTLD in the skin are usually linked with lymph node or other organ involvement.Methods:  We report a case of plasmacytoid PTLD that is limited to the skin. A 63-year-old man with a history of cardiac transplant presented with exophytic tumors involving the lower extremity. The diagnosis and classification of the various forms of PTLD are discussed.Results:  Histology, immunohistochemical stains, and in situ hybridization revealed an aggressive plasmacytoid tumor that was Epstein–Barr virus positive. The patient's tumors resolved with decreased immunosuppression and localized radiation.Conclusion:  This case is unusual for several reasons including involvement limited to the skin, presentation 15 years following transplant, and plasmacytoid phenotype of the tumor. This disorder will likely be seen by dermatologists and dermatopathologists with the increasing use of immunosuppressive medications in the dermatologist's patient population.
1600-0560
16000560
shingle_catch_all_4 Samolitis, Nancy J.
Bharadwaj, Jayaram S.
Weis, John R.
Harris, Ronald M.
Post-transplant lymphoproliferative disorder limited to the skin
Munksgaard International Publishers
Background:  Post-transplant lymphoproliferative disorder (PTLD) is a condition affecting immunosuppressed transplant patients and has a variety of clinical presentations. It is rarely found in the skin, and cases of PTLD in the skin are usually linked with lymph node or other organ involvement.Methods:  We report a case of plasmacytoid PTLD that is limited to the skin. A 63-year-old man with a history of cardiac transplant presented with exophytic tumors involving the lower extremity. The diagnosis and classification of the various forms of PTLD are discussed.Results:  Histology, immunohistochemical stains, and in situ hybridization revealed an aggressive plasmacytoid tumor that was Epstein–Barr virus positive. The patient's tumors resolved with decreased immunosuppression and localized radiation.Conclusion:  This case is unusual for several reasons including involvement limited to the skin, presentation 15 years following transplant, and plasmacytoid phenotype of the tumor. This disorder will likely be seen by dermatologists and dermatopathologists with the increasing use of immunosuppressive medications in the dermatologist's patient population.
1600-0560
16000560
shingle_title_1 Post-transplant lymphoproliferative disorder limited to the skin
shingle_title_2 Post-transplant lymphoproliferative disorder limited to the skin
shingle_title_3 Post-transplant lymphoproliferative disorder limited to the skin
shingle_title_4 Post-transplant lymphoproliferative disorder limited to the skin
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source_archive Blackwell Publishing Journal Backfiles 1879-2005
timestamp 2024-05-06T08:17:30.986Z
titel Post-transplant lymphoproliferative disorder limited to the skin
titel_suche Post-transplant lymphoproliferative disorder limited to the skin
topic WW-YZ
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