Use of diclofenac in children with asthma
Short, J. A. ; Barr, C. A. ; Palmer, C. D. ; Goddard, J. M. ; Stack, C. G. ; Primhak, R. A.
Oxford : Blackwell Science Ltd
Published 2000
Oxford : Blackwell Science Ltd
Published 2000
| ISSN: |
1365-2044
|
|---|---|
| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
|
| Topics: |
Medicine
|
| Notes: |
This study investigated the effect of diclofenac on the lung function of 70 children aged 6–15 years with a diagnosis of asthma, recruited from a hospital respiratory clinic. Peak flow and a forced expiratory flow-volume loop were measured and the patients were then given 1–1.5 mg.kg−1 effervescent diclofenac orally. Spirometry was repeated at 10, 20 and 30 min, a 15% decrease in results being considered a significant reduction in lung function. No patient demonstrated a consistent reduction in lung function of 〉 15% during the study and there were no reports of wheezing or increased bronchodilator use after completion of the spirometry. In conclusion, we studied a group of genuine asthmatics and found no clinically significant incidence of bronchospasm with the use of a single therapeutic dose of diclofenac.
|
| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798290188117475328 |
|---|---|
| autor | Short, J. A. Barr, C. A. Palmer, C. D. Goddard, J. M. Stack, C. G. Primhak, R. A. |
| autorsonst | Goddard, J. M. Stack, C. G. Primhak, R. A. |
| book_url | http://dx.doi.org/10.1046/j.1365-2044.2000.01280.x |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLZ24226977X |
| insertion_date | 2012-04-27 |
| issn | 1365-2044 |
| journal_name | Anaesthesia |
| materialart | 1 |
| notes | This study investigated the effect of diclofenac on the lung function of 70 children aged 6–15 years with a diagnosis of asthma, recruited from a hospital respiratory clinic. Peak flow and a forced expiratory flow-volume loop were measured and the patients were then given 1–1.5 mg.kg−1 effervescent diclofenac orally. Spirometry was repeated at 10, 20 and 30 min, a 15% decrease in results being considered a significant reduction in lung function. No patient demonstrated a consistent reduction in lung function of 〉 15% during the study and there were no reports of wheezing or increased bronchodilator use after completion of the spirometry. In conclusion, we studied a group of genuine asthmatics and found no clinically significant incidence of bronchospasm with the use of a single therapeutic dose of diclofenac. |
| package_name | Blackwell Publishing |
| publikationsjahr_anzeige | 2000 |
| publikationsjahr_facette | 2000 |
| publikationsjahr_intervall | 7999:2000-2004 |
| publikationsjahr_sort | 2000 |
| publikationsort | Oxford |
| publisher | Blackwell Science Ltd |
| reference | 55 (2000), S. 0 |
| search_space | articles |
| shingle_author_1 | Short, J. A. Barr, C. A. Palmer, C. D. Goddard, J. M. Stack, C. G. Primhak, R. A. |
| shingle_author_2 | Short, J. A. Barr, C. A. Palmer, C. D. Goddard, J. M. Stack, C. G. Primhak, R. A. |
| shingle_author_3 | Short, J. A. Barr, C. A. Palmer, C. D. Goddard, J. M. Stack, C. G. Primhak, R. A. |
| shingle_author_4 | Short, J. A. Barr, C. A. Palmer, C. D. Goddard, J. M. Stack, C. G. Primhak, R. A. |
| shingle_catch_all_1 | Short, J. A. Barr, C. A. Palmer, C. D. Goddard, J. M. Stack, C. G. Primhak, R. A. Use of diclofenac in children with asthma Blackwell Science Ltd This study investigated the effect of diclofenac on the lung function of 70 children aged 6–15 years with a diagnosis of asthma, recruited from a hospital respiratory clinic. Peak flow and a forced expiratory flow-volume loop were measured and the patients were then given 1–1.5 mg.kg−1 effervescent diclofenac orally. Spirometry was repeated at 10, 20 and 30 min, a 15% decrease in results being considered a significant reduction in lung function. No patient demonstrated a consistent reduction in lung function of 〉 15% during the study and there were no reports of wheezing or increased bronchodilator use after completion of the spirometry. In conclusion, we studied a group of genuine asthmatics and found no clinically significant incidence of bronchospasm with the use of a single therapeutic dose of diclofenac. 1365-2044 13652044 |
| shingle_catch_all_2 | Short, J. A. Barr, C. A. Palmer, C. D. Goddard, J. M. Stack, C. G. Primhak, R. A. Use of diclofenac in children with asthma Blackwell Science Ltd This study investigated the effect of diclofenac on the lung function of 70 children aged 6–15 years with a diagnosis of asthma, recruited from a hospital respiratory clinic. Peak flow and a forced expiratory flow-volume loop were measured and the patients were then given 1–1.5 mg.kg−1 effervescent diclofenac orally. Spirometry was repeated at 10, 20 and 30 min, a 15% decrease in results being considered a significant reduction in lung function. No patient demonstrated a consistent reduction in lung function of 〉 15% during the study and there were no reports of wheezing or increased bronchodilator use after completion of the spirometry. In conclusion, we studied a group of genuine asthmatics and found no clinically significant incidence of bronchospasm with the use of a single therapeutic dose of diclofenac. 1365-2044 13652044 |
| shingle_catch_all_3 | Short, J. A. Barr, C. A. Palmer, C. D. Goddard, J. M. Stack, C. G. Primhak, R. A. Use of diclofenac in children with asthma Blackwell Science Ltd This study investigated the effect of diclofenac on the lung function of 70 children aged 6–15 years with a diagnosis of asthma, recruited from a hospital respiratory clinic. Peak flow and a forced expiratory flow-volume loop were measured and the patients were then given 1–1.5 mg.kg−1 effervescent diclofenac orally. Spirometry was repeated at 10, 20 and 30 min, a 15% decrease in results being considered a significant reduction in lung function. No patient demonstrated a consistent reduction in lung function of 〉 15% during the study and there were no reports of wheezing or increased bronchodilator use after completion of the spirometry. In conclusion, we studied a group of genuine asthmatics and found no clinically significant incidence of bronchospasm with the use of a single therapeutic dose of diclofenac. 1365-2044 13652044 |
| shingle_catch_all_4 | Short, J. A. Barr, C. A. Palmer, C. D. Goddard, J. M. Stack, C. G. Primhak, R. A. Use of diclofenac in children with asthma Blackwell Science Ltd This study investigated the effect of diclofenac on the lung function of 70 children aged 6–15 years with a diagnosis of asthma, recruited from a hospital respiratory clinic. Peak flow and a forced expiratory flow-volume loop were measured and the patients were then given 1–1.5 mg.kg−1 effervescent diclofenac orally. Spirometry was repeated at 10, 20 and 30 min, a 15% decrease in results being considered a significant reduction in lung function. No patient demonstrated a consistent reduction in lung function of 〉 15% during the study and there were no reports of wheezing or increased bronchodilator use after completion of the spirometry. In conclusion, we studied a group of genuine asthmatics and found no clinically significant incidence of bronchospasm with the use of a single therapeutic dose of diclofenac. 1365-2044 13652044 |
| shingle_title_1 | Use of diclofenac in children with asthma |
| shingle_title_2 | Use of diclofenac in children with asthma |
| shingle_title_3 | Use of diclofenac in children with asthma |
| shingle_title_4 | Use of diclofenac in children with asthma |
| sigel_instance_filter | dkfz geomar wilbert ipn albert |
| source_archive | Blackwell Publishing Journal Backfiles 1879-2005 |
| timestamp | 2024-05-06T08:12:45.115Z |
| titel | Use of diclofenac in children with asthma |
| titel_suche | Use of diclofenac in children with asthma |
| topic | WW-YZ |
| uid | nat_lic_papers_NLZ24226977X |