Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions
Tanioka, M. ; Ikoma, A. ; Morita, K. ; Fujii, H. ; Toda, K-I. ; Takahashi, K. ; Tanaka, T. ; Nishigori, C. ; Jin, G. ; Higashi, S. ; Toyokuni, S. ; Miyachi, Y.
Oxford, UK : Blackwell Science Ltd
Published 2001
Oxford, UK : Blackwell Science Ltd
Published 2001
| ISSN: |
1365-2133
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|---|---|
| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
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| Topics: |
Medicine
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| Notes: |
A 73-year-old man with angiosarcoma of the scalp died about 1 year after disease onset, despite systemic and topical administration of recombinant interleukin-2. Histopathology showed typical changes of endothelial cells with very sparse lymphocytic infiltration into the tumour. An autopsy revealed that the primary site penetrated cranial bone and invaded vertically into the subarachnoid space. Multiple metastases to lung, chest wall, vertebrae and ribs were also found. On immunofluorescence staining, the expression of vascular endothelial cadherin, which is present in normal endothelium, was absent from both primary and metastatic sites. This may have promoted local invasion and metastasis.
|
| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798290095252439040 |
|---|---|
| autor | Tanioka, M. Ikoma, A. Morita, K. Fujii, H. Toda, K-I. Takahashi, K. Tanaka, T. Nishigori, C. Jin, G. Higashi, S. Toyokuni, S. Miyachi, Y. |
| autorsonst | Tanioka, M. Ikoma, A. Morita, K. Fujii, H. Toda, K-I. Takahashi, K. Tanaka, T. Nishigori, C. Jin, G. Higashi, S. Toyokuni, S. Miyachi, Y. |
| book_url | http://dx.doi.org/10.1046/j.1365-2133.2001.04032.x |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLZ242131921 |
| insertion_date | 2012-04-27 |
| issn | 1365-2133 |
| journal_name | British journal of dermatology |
| materialart | 1 |
| notes | A 73-year-old man with angiosarcoma of the scalp died about 1 year after disease onset, despite systemic and topical administration of recombinant interleukin-2. Histopathology showed typical changes of endothelial cells with very sparse lymphocytic infiltration into the tumour. An autopsy revealed that the primary site penetrated cranial bone and invaded vertically into the subarachnoid space. Multiple metastases to lung, chest wall, vertebrae and ribs were also found. On immunofluorescence staining, the expression of vascular endothelial cadherin, which is present in normal endothelium, was absent from both primary and metastatic sites. This may have promoted local invasion and metastasis. |
| package_name | Blackwell Publishing |
| publikationsjahr_anzeige | 2001 |
| publikationsjahr_facette | 2001 |
| publikationsjahr_intervall | 7999:2000-2004 |
| publikationsjahr_sort | 2001 |
| publikationsort | Oxford, UK |
| publisher | Blackwell Science Ltd |
| reference | 144 (2001), S. 0 |
| search_space | articles |
| shingle_author_1 | Tanioka, M. Ikoma, A. Morita, K. Fujii, H. Toda, K-I. Takahashi, K. Tanaka, T. Nishigori, C. Jin, G. Higashi, S. Toyokuni, S. Miyachi, Y. |
| shingle_author_2 | Tanioka, M. Ikoma, A. Morita, K. Fujii, H. Toda, K-I. Takahashi, K. Tanaka, T. Nishigori, C. Jin, G. Higashi, S. Toyokuni, S. Miyachi, Y. |
| shingle_author_3 | Tanioka, M. Ikoma, A. Morita, K. Fujii, H. Toda, K-I. Takahashi, K. Tanaka, T. Nishigori, C. Jin, G. Higashi, S. Toyokuni, S. Miyachi, Y. |
| shingle_author_4 | Tanioka, M. Ikoma, A. Morita, K. Fujii, H. Toda, K-I. Takahashi, K. Tanaka, T. Nishigori, C. Jin, G. Higashi, S. Toyokuni, S. Miyachi, Y. |
| shingle_catch_all_1 | Tanioka, M. Ikoma, A. Morita, K. Fujii, H. Toda, K-I. Takahashi, K. Tanaka, T. Nishigori, C. Jin, G. Higashi, S. Toyokuni, S. Miyachi, Y. Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions Blackwell Science Ltd A 73-year-old man with angiosarcoma of the scalp died about 1 year after disease onset, despite systemic and topical administration of recombinant interleukin-2. Histopathology showed typical changes of endothelial cells with very sparse lymphocytic infiltration into the tumour. An autopsy revealed that the primary site penetrated cranial bone and invaded vertically into the subarachnoid space. Multiple metastases to lung, chest wall, vertebrae and ribs were also found. On immunofluorescence staining, the expression of vascular endothelial cadherin, which is present in normal endothelium, was absent from both primary and metastatic sites. This may have promoted local invasion and metastasis. 1365-2133 13652133 |
| shingle_catch_all_2 | Tanioka, M. Ikoma, A. Morita, K. Fujii, H. Toda, K-I. Takahashi, K. Tanaka, T. Nishigori, C. Jin, G. Higashi, S. Toyokuni, S. Miyachi, Y. Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions Blackwell Science Ltd A 73-year-old man with angiosarcoma of the scalp died about 1 year after disease onset, despite systemic and topical administration of recombinant interleukin-2. Histopathology showed typical changes of endothelial cells with very sparse lymphocytic infiltration into the tumour. An autopsy revealed that the primary site penetrated cranial bone and invaded vertically into the subarachnoid space. Multiple metastases to lung, chest wall, vertebrae and ribs were also found. On immunofluorescence staining, the expression of vascular endothelial cadherin, which is present in normal endothelium, was absent from both primary and metastatic sites. This may have promoted local invasion and metastasis. 1365-2133 13652133 |
| shingle_catch_all_3 | Tanioka, M. Ikoma, A. Morita, K. Fujii, H. Toda, K-I. Takahashi, K. Tanaka, T. Nishigori, C. Jin, G. Higashi, S. Toyokuni, S. Miyachi, Y. Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions Blackwell Science Ltd A 73-year-old man with angiosarcoma of the scalp died about 1 year after disease onset, despite systemic and topical administration of recombinant interleukin-2. Histopathology showed typical changes of endothelial cells with very sparse lymphocytic infiltration into the tumour. An autopsy revealed that the primary site penetrated cranial bone and invaded vertically into the subarachnoid space. Multiple metastases to lung, chest wall, vertebrae and ribs were also found. On immunofluorescence staining, the expression of vascular endothelial cadherin, which is present in normal endothelium, was absent from both primary and metastatic sites. This may have promoted local invasion and metastasis. 1365-2133 13652133 |
| shingle_catch_all_4 | Tanioka, M. Ikoma, A. Morita, K. Fujii, H. Toda, K-I. Takahashi, K. Tanaka, T. Nishigori, C. Jin, G. Higashi, S. Toyokuni, S. Miyachi, Y. Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions Blackwell Science Ltd A 73-year-old man with angiosarcoma of the scalp died about 1 year after disease onset, despite systemic and topical administration of recombinant interleukin-2. Histopathology showed typical changes of endothelial cells with very sparse lymphocytic infiltration into the tumour. An autopsy revealed that the primary site penetrated cranial bone and invaded vertically into the subarachnoid space. Multiple metastases to lung, chest wall, vertebrae and ribs were also found. On immunofluorescence staining, the expression of vascular endothelial cadherin, which is present in normal endothelium, was absent from both primary and metastatic sites. This may have promoted local invasion and metastasis. 1365-2133 13652133 |
| shingle_title_1 | Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions |
| shingle_title_2 | Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions |
| shingle_title_3 | Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions |
| shingle_title_4 | Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions |
| sigel_instance_filter | dkfz geomar wilbert ipn albert |
| source_archive | Blackwell Publishing Journal Backfiles 1879-2005 |
| timestamp | 2024-05-06T08:11:17.064Z |
| titel | Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions |
| titel_suche | Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions |
| topic | WW-YZ |
| uid | nat_lic_papers_NLZ242131921 |