Unique sequences in region VI of the flagellin gene of Salmonella typhi
Frankel, G. ; Newton, S. M. C. ; Schoolnik, G. K. ; Stocker, B. A. D.
Oxford, UK : Blackwell Publishing Ltd
Published 1989
Oxford, UK : Blackwell Publishing Ltd
Published 1989
| ISSN: |
1365-2958
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|---|---|
| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
|
| Topics: |
Biology
Medicine
|
| Notes: |
The HI (now renamed fliC; lino et al., 1988) alleles specifying antigenically different Salmonella flagellins are identical at their ends but differ greatly towards the middle, where there are two hypervariable segments (regions IV and VI). The flagellar antigen, d, of Salmonella typhi, is found also as phase-1 antigen in many other Saimonella species. We cloned the H1-d gene of a strain of S. typhi and determined the nucleotide sequence of its two hypervariable regions. Comparison with gene H1-d of Salmonella muenchen showed substantial differences in region VI: four scattered amino acid differences and ten adjacent amino acids in the inferred S. typhi sequence, all of which differ from the corresponding nine amino acids in the S. muenchen sequence. The results of polymerase chain reaction amplification indicated the presence of the S. typhi version in all of 18 additional S. typhi strains and the presence of the S. muenchen version in all four non-S. typhi species with flagellar antigen d. The difference in amino acid sequence in segment VI may be responsible for the minor serological differences between antigens d of S. typhi and antigen d of S. muenchen.
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| Type of Medium: |
Electronic Resource
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| URL: |
| _version_ | 1798290416237281280 |
|---|---|
| autor | Frankel, G. Newton, S. M. C. Schoolnik, G. K. Stocker, B. A. D. |
| autorsonst | Stocker, B. A. D. |
| book_url | http://dx.doi.org/10.1111/j.1365-2958.1989.tb00119.x |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLZ241780888 |
| insertion_date | 2012-04-27 |
| issn | 1365-2958 |
| journal_name | Molecular microbiology |
| materialart | 1 |
| notes | The HI (now renamed fliC; lino et al., 1988) alleles specifying antigenically different Salmonella flagellins are identical at their ends but differ greatly towards the middle, where there are two hypervariable segments (regions IV and VI). The flagellar antigen, d, of Salmonella typhi, is found also as phase-1 antigen in many other Saimonella species. We cloned the H1-d gene of a strain of S. typhi and determined the nucleotide sequence of its two hypervariable regions. Comparison with gene H1-d of Salmonella muenchen showed substantial differences in region VI: four scattered amino acid differences and ten adjacent amino acids in the inferred S. typhi sequence, all of which differ from the corresponding nine amino acids in the S. muenchen sequence. The results of polymerase chain reaction amplification indicated the presence of the S. typhi version in all of 18 additional S. typhi strains and the presence of the S. muenchen version in all four non-S. typhi species with flagellar antigen d. The difference in amino acid sequence in segment VI may be responsible for the minor serological differences between antigens d of S. typhi and antigen d of S. muenchen. |
| package_name | Blackwell Publishing |
| publikationsjahr_anzeige | 1989 |
| publikationsjahr_facette | 1989 |
| publikationsjahr_intervall | 8014:1985-1989 |
| publikationsjahr_sort | 1989 |
| publikationsort | Oxford, UK |
| publisher | Blackwell Publishing Ltd |
| reference | 3 (1989), S. 0 |
| search_space | articles |
| shingle_author_1 | Frankel, G. Newton, S. M. C. Schoolnik, G. K. Stocker, B. A. D. |
| shingle_author_2 | Frankel, G. Newton, S. M. C. Schoolnik, G. K. Stocker, B. A. D. |
| shingle_author_3 | Frankel, G. Newton, S. M. C. Schoolnik, G. K. Stocker, B. A. D. |
| shingle_author_4 | Frankel, G. Newton, S. M. C. Schoolnik, G. K. Stocker, B. A. D. |
| shingle_catch_all_1 | Frankel, G. Newton, S. M. C. Schoolnik, G. K. Stocker, B. A. D. Unique sequences in region VI of the flagellin gene of Salmonella typhi Blackwell Publishing Ltd The HI (now renamed fliC; lino et al., 1988) alleles specifying antigenically different Salmonella flagellins are identical at their ends but differ greatly towards the middle, where there are two hypervariable segments (regions IV and VI). The flagellar antigen, d, of Salmonella typhi, is found also as phase-1 antigen in many other Saimonella species. We cloned the H1-d gene of a strain of S. typhi and determined the nucleotide sequence of its two hypervariable regions. Comparison with gene H1-d of Salmonella muenchen showed substantial differences in region VI: four scattered amino acid differences and ten adjacent amino acids in the inferred S. typhi sequence, all of which differ from the corresponding nine amino acids in the S. muenchen sequence. The results of polymerase chain reaction amplification indicated the presence of the S. typhi version in all of 18 additional S. typhi strains and the presence of the S. muenchen version in all four non-S. typhi species with flagellar antigen d. The difference in amino acid sequence in segment VI may be responsible for the minor serological differences between antigens d of S. typhi and antigen d of S. muenchen. 1365-2958 13652958 |
| shingle_catch_all_2 | Frankel, G. Newton, S. M. C. Schoolnik, G. K. Stocker, B. A. D. Unique sequences in region VI of the flagellin gene of Salmonella typhi Blackwell Publishing Ltd The HI (now renamed fliC; lino et al., 1988) alleles specifying antigenically different Salmonella flagellins are identical at their ends but differ greatly towards the middle, where there are two hypervariable segments (regions IV and VI). The flagellar antigen, d, of Salmonella typhi, is found also as phase-1 antigen in many other Saimonella species. We cloned the H1-d gene of a strain of S. typhi and determined the nucleotide sequence of its two hypervariable regions. Comparison with gene H1-d of Salmonella muenchen showed substantial differences in region VI: four scattered amino acid differences and ten adjacent amino acids in the inferred S. typhi sequence, all of which differ from the corresponding nine amino acids in the S. muenchen sequence. The results of polymerase chain reaction amplification indicated the presence of the S. typhi version in all of 18 additional S. typhi strains and the presence of the S. muenchen version in all four non-S. typhi species with flagellar antigen d. The difference in amino acid sequence in segment VI may be responsible for the minor serological differences between antigens d of S. typhi and antigen d of S. muenchen. 1365-2958 13652958 |
| shingle_catch_all_3 | Frankel, G. Newton, S. M. C. Schoolnik, G. K. Stocker, B. A. D. Unique sequences in region VI of the flagellin gene of Salmonella typhi Blackwell Publishing Ltd The HI (now renamed fliC; lino et al., 1988) alleles specifying antigenically different Salmonella flagellins are identical at their ends but differ greatly towards the middle, where there are two hypervariable segments (regions IV and VI). The flagellar antigen, d, of Salmonella typhi, is found also as phase-1 antigen in many other Saimonella species. We cloned the H1-d gene of a strain of S. typhi and determined the nucleotide sequence of its two hypervariable regions. Comparison with gene H1-d of Salmonella muenchen showed substantial differences in region VI: four scattered amino acid differences and ten adjacent amino acids in the inferred S. typhi sequence, all of which differ from the corresponding nine amino acids in the S. muenchen sequence. The results of polymerase chain reaction amplification indicated the presence of the S. typhi version in all of 18 additional S. typhi strains and the presence of the S. muenchen version in all four non-S. typhi species with flagellar antigen d. The difference in amino acid sequence in segment VI may be responsible for the minor serological differences between antigens d of S. typhi and antigen d of S. muenchen. 1365-2958 13652958 |
| shingle_catch_all_4 | Frankel, G. Newton, S. M. C. Schoolnik, G. K. Stocker, B. A. D. Unique sequences in region VI of the flagellin gene of Salmonella typhi Blackwell Publishing Ltd The HI (now renamed fliC; lino et al., 1988) alleles specifying antigenically different Salmonella flagellins are identical at their ends but differ greatly towards the middle, where there are two hypervariable segments (regions IV and VI). The flagellar antigen, d, of Salmonella typhi, is found also as phase-1 antigen in many other Saimonella species. We cloned the H1-d gene of a strain of S. typhi and determined the nucleotide sequence of its two hypervariable regions. Comparison with gene H1-d of Salmonella muenchen showed substantial differences in region VI: four scattered amino acid differences and ten adjacent amino acids in the inferred S. typhi sequence, all of which differ from the corresponding nine amino acids in the S. muenchen sequence. The results of polymerase chain reaction amplification indicated the presence of the S. typhi version in all of 18 additional S. typhi strains and the presence of the S. muenchen version in all four non-S. typhi species with flagellar antigen d. The difference in amino acid sequence in segment VI may be responsible for the minor serological differences between antigens d of S. typhi and antigen d of S. muenchen. 1365-2958 13652958 |
| shingle_title_1 | Unique sequences in region VI of the flagellin gene of Salmonella typhi |
| shingle_title_2 | Unique sequences in region VI of the flagellin gene of Salmonella typhi |
| shingle_title_3 | Unique sequences in region VI of the flagellin gene of Salmonella typhi |
| shingle_title_4 | Unique sequences in region VI of the flagellin gene of Salmonella typhi |
| sigel_instance_filter | dkfz geomar wilbert ipn albert |
| source_archive | Blackwell Publishing Journal Backfiles 1879-2005 |
| timestamp | 2024-05-06T08:16:23.097Z |
| titel | Unique sequences in region VI of the flagellin gene of Salmonella typhi |
| titel_suche | Unique sequences in region VI of the flagellin gene of Salmonella typhi |
| topic | W WW-YZ |
| uid | nat_lic_papers_NLZ241780888 |