Studies on Clostridium acetobutylicum ginA promoters and antisense RNA
| ISSN: |
1365-2958
|
|---|---|
| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
|
| Topics: |
Biology
Medicine
|
| Notes: |
The Clostridium acetobutylicum glnA gene has two transcript start sites under the control of promoters P1 and p2. Initiation of transcription was regulated by nitrogen and a downstream region was implicated in the regulation of transcript initiation by nitrogen in Escherichia coli. Putative antisense RNA was produced from a single downstream transcript start site under the control of P3. An up-promoter mutation in P3 resulted in lower levels of glutamine synthetase (GS) activity. Putative antisense RNA had a role in down-regulating GS expression but was not involved in regulation by nitrogen. Deletion of downstream inverted repeat sequences resulted in very low levels of GS activity.
|
| Type of Medium: |
Electronic Resource
|
| URL: |