Mitochondrial gene sequences show fungal homology for Pneumocystis carinii
Pixley, F. J. ; Wakefield, A. E. ; Banerji, S. ; Hopkin, J. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1991
Oxford, UK : Blackwell Publishing Ltd
Published 1991
ISSN: |
1365-2958
|
---|---|
Source: |
Blackwell Publishing Journal Backfiles 1879-2005
|
Topics: |
Biology
Medicine
|
Notes: |
A 6.8 kjlobase fragment of mJtochondrial DNA from Pneumocystis carinii encodes for apocytochrome b, NADH dehydrogenase subunits 1, 2, 3, and 6, cytochrome oxidase subunit II, and the small subunit of ribosomal RNA. Comparative sequence analysis with a series of organisms representative of the fungal and protozoan groups shows that R carinii has, consistently, an average similarity of 60% with the fungi but only 20% with the protozoa. The data indicate homology with the fungi for this opportunistic pathogen.
|
Type of Medium: |
Electronic Resource
|
URL: |