PHOSPHOLIPID METABOLISM IN CULTURED NEUROBLASTOMA AND GLIOMA CELLS INCUBATED WITH CARBAMYLCHOLINE AND NOREPINEPHRINE
| ISSN: |
1471-4159
|
|---|---|
| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
|
| Topics: |
Medicine
|
| Notes: |
Cultures of cloned neuroblastoma cells (N1E) in stationary phase and cloned glioma cells (C21) in confluency showed substantial differences in phospholipid composition. As a percentage of lipid P, N1E contained more phosphatidylcholine, less ethanolamine phosphoglycerides and much less sphingomyelin than C21. When incubated with 32Pi both cell lines incorporated comparable amounts of radioactivity into total phospholipids. In NIE, phosphatidylcholine contained much more and phosphatidylinositol and phosphatidic acid somewhat less label as compared to C21. The presence in the incubation medium of either norepinephrine or carbamylcholine failed to elicit stimulation of 32P incorporation into any phospholipid class.
|
| Type of Medium: |
Electronic Resource
|
| URL: |