Extended radical hysterectomy in early-stage carcinoma of the uterine cervix: tailoring the radicality
Sartori, E. ; Fallo, L. ; La Face, B. ; Bianchi, U.A. ; Pecorelli, S.
Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachussetts 02142, USA : Blackwell Science Inc.
Published 1995
Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachussetts 02142, USA : Blackwell Science Inc.
Published 1995
| ISSN: |
1525-1438
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|---|---|
| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
|
| Topics: |
Medicine
|
| Notes: |
The question of whether surgical treatment in early-stage cervical cancer should be aggressive or restricted to less radical techniques is still controversial. To answer this question it was thought useful to investigate the correlation of parametrial lymph node metastases with extension and stage of disease. Two-hundred and sixty-three consecutive primary radical surgical procedures were performed in our institute in clinical stage IB or stage IIA cervical cancer. Positive parametrial nodes were found in 6.9% of cases: 5% in stage IB (3% in the proximal part of the parametrium and 2% in the distal part, near the pelvic wall) and 16.3% in stage IIA (7% proximal and 9.3% distal) (P = 0.0193). During a median follow-up period of 92 months, disease recurred in 17.1% and 17.6% of cases, in negative and positive parametria, respectively. The 5-year overall and disease-free survival rates were 80.4% and 81.6% for patients with negative and positive parametria, respectively. From this experience it is concluded that the extent of radical hysterectomy should be related to the extent of the disease on the basis of modern knowledge of the pattern of spread. The principal key to prognosis remains pelvic and paracavoaortic nodal status.
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| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798290029132382209 |
|---|---|
| autor | Sartori, E. Fallo, L. La Face, B. Bianchi, U.A. Pecorelli, S. |
| autorsonst | Bianchi, U.A. Pecorelli, S. |
| book_url | http://dx.doi.org/10.1046/j.1525-1438.1995.05020143.x |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLZ239409779 |
| insertion_date | 2012-04-26 |
| issn | 1525-1438 |
| journal_name | International journal of gynecological cancer |
| materialart | 1 |
| notes | The question of whether surgical treatment in early-stage cervical cancer should be aggressive or restricted to less radical techniques is still controversial. To answer this question it was thought useful to investigate the correlation of parametrial lymph node metastases with extension and stage of disease. Two-hundred and sixty-three consecutive primary radical surgical procedures were performed in our institute in clinical stage IB or stage IIA cervical cancer. Positive parametrial nodes were found in 6.9% of cases: 5% in stage IB (3% in the proximal part of the parametrium and 2% in the distal part, near the pelvic wall) and 16.3% in stage IIA (7% proximal and 9.3% distal) (P = 0.0193). During a median follow-up period of 92 months, disease recurred in 17.1% and 17.6% of cases, in negative and positive parametria, respectively. The 5-year overall and disease-free survival rates were 80.4% and 81.6% for patients with negative and positive parametria, respectively. From this experience it is concluded that the extent of radical hysterectomy should be related to the extent of the disease on the basis of modern knowledge of the pattern of spread. The principal key to prognosis remains pelvic and paracavoaortic nodal status. |
| package_name | Blackwell Publishing |
| publikationsjahr_anzeige | 1995 |
| publikationsjahr_facette | 1995 |
| publikationsjahr_intervall | 8004:1995-1999 |
| publikationsjahr_sort | 1995 |
| publikationsort | Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachussetts 02142, USA |
| publisher | Blackwell Science Inc. |
| reference | 5 (1995), S. 0 |
| search_space | articles |
| shingle_author_1 | Sartori, E. Fallo, L. La Face, B. Bianchi, U.A. Pecorelli, S. |
| shingle_author_2 | Sartori, E. Fallo, L. La Face, B. Bianchi, U.A. Pecorelli, S. |
| shingle_author_3 | Sartori, E. Fallo, L. La Face, B. Bianchi, U.A. Pecorelli, S. |
| shingle_author_4 | Sartori, E. Fallo, L. La Face, B. Bianchi, U.A. Pecorelli, S. |
| shingle_catch_all_1 | Sartori, E. Fallo, L. La Face, B. Bianchi, U.A. Pecorelli, S. Extended radical hysterectomy in early-stage carcinoma of the uterine cervix: tailoring the radicality Blackwell Science Inc. The question of whether surgical treatment in early-stage cervical cancer should be aggressive or restricted to less radical techniques is still controversial. To answer this question it was thought useful to investigate the correlation of parametrial lymph node metastases with extension and stage of disease. Two-hundred and sixty-three consecutive primary radical surgical procedures were performed in our institute in clinical stage IB or stage IIA cervical cancer. Positive parametrial nodes were found in 6.9% of cases: 5% in stage IB (3% in the proximal part of the parametrium and 2% in the distal part, near the pelvic wall) and 16.3% in stage IIA (7% proximal and 9.3% distal) (P = 0.0193). During a median follow-up period of 92 months, disease recurred in 17.1% and 17.6% of cases, in negative and positive parametria, respectively. The 5-year overall and disease-free survival rates were 80.4% and 81.6% for patients with negative and positive parametria, respectively. From this experience it is concluded that the extent of radical hysterectomy should be related to the extent of the disease on the basis of modern knowledge of the pattern of spread. The principal key to prognosis remains pelvic and paracavoaortic nodal status. 1525-1438 15251438 |
| shingle_catch_all_2 | Sartori, E. Fallo, L. La Face, B. Bianchi, U.A. Pecorelli, S. Extended radical hysterectomy in early-stage carcinoma of the uterine cervix: tailoring the radicality Blackwell Science Inc. The question of whether surgical treatment in early-stage cervical cancer should be aggressive or restricted to less radical techniques is still controversial. To answer this question it was thought useful to investigate the correlation of parametrial lymph node metastases with extension and stage of disease. Two-hundred and sixty-three consecutive primary radical surgical procedures were performed in our institute in clinical stage IB or stage IIA cervical cancer. Positive parametrial nodes were found in 6.9% of cases: 5% in stage IB (3% in the proximal part of the parametrium and 2% in the distal part, near the pelvic wall) and 16.3% in stage IIA (7% proximal and 9.3% distal) (P = 0.0193). During a median follow-up period of 92 months, disease recurred in 17.1% and 17.6% of cases, in negative and positive parametria, respectively. The 5-year overall and disease-free survival rates were 80.4% and 81.6% for patients with negative and positive parametria, respectively. From this experience it is concluded that the extent of radical hysterectomy should be related to the extent of the disease on the basis of modern knowledge of the pattern of spread. The principal key to prognosis remains pelvic and paracavoaortic nodal status. 1525-1438 15251438 |
| shingle_catch_all_3 | Sartori, E. Fallo, L. La Face, B. Bianchi, U.A. Pecorelli, S. Extended radical hysterectomy in early-stage carcinoma of the uterine cervix: tailoring the radicality Blackwell Science Inc. The question of whether surgical treatment in early-stage cervical cancer should be aggressive or restricted to less radical techniques is still controversial. To answer this question it was thought useful to investigate the correlation of parametrial lymph node metastases with extension and stage of disease. Two-hundred and sixty-three consecutive primary radical surgical procedures were performed in our institute in clinical stage IB or stage IIA cervical cancer. Positive parametrial nodes were found in 6.9% of cases: 5% in stage IB (3% in the proximal part of the parametrium and 2% in the distal part, near the pelvic wall) and 16.3% in stage IIA (7% proximal and 9.3% distal) (P = 0.0193). During a median follow-up period of 92 months, disease recurred in 17.1% and 17.6% of cases, in negative and positive parametria, respectively. The 5-year overall and disease-free survival rates were 80.4% and 81.6% for patients with negative and positive parametria, respectively. From this experience it is concluded that the extent of radical hysterectomy should be related to the extent of the disease on the basis of modern knowledge of the pattern of spread. The principal key to prognosis remains pelvic and paracavoaortic nodal status. 1525-1438 15251438 |
| shingle_catch_all_4 | Sartori, E. Fallo, L. La Face, B. Bianchi, U.A. Pecorelli, S. Extended radical hysterectomy in early-stage carcinoma of the uterine cervix: tailoring the radicality Blackwell Science Inc. The question of whether surgical treatment in early-stage cervical cancer should be aggressive or restricted to less radical techniques is still controversial. To answer this question it was thought useful to investigate the correlation of parametrial lymph node metastases with extension and stage of disease. Two-hundred and sixty-three consecutive primary radical surgical procedures were performed in our institute in clinical stage IB or stage IIA cervical cancer. Positive parametrial nodes were found in 6.9% of cases: 5% in stage IB (3% in the proximal part of the parametrium and 2% in the distal part, near the pelvic wall) and 16.3% in stage IIA (7% proximal and 9.3% distal) (P = 0.0193). During a median follow-up period of 92 months, disease recurred in 17.1% and 17.6% of cases, in negative and positive parametria, respectively. The 5-year overall and disease-free survival rates were 80.4% and 81.6% for patients with negative and positive parametria, respectively. From this experience it is concluded that the extent of radical hysterectomy should be related to the extent of the disease on the basis of modern knowledge of the pattern of spread. The principal key to prognosis remains pelvic and paracavoaortic nodal status. 1525-1438 15251438 |
| shingle_title_1 | Extended radical hysterectomy in early-stage carcinoma of the uterine cervix: tailoring the radicality |
| shingle_title_2 | Extended radical hysterectomy in early-stage carcinoma of the uterine cervix: tailoring the radicality |
| shingle_title_3 | Extended radical hysterectomy in early-stage carcinoma of the uterine cervix: tailoring the radicality |
| shingle_title_4 | Extended radical hysterectomy in early-stage carcinoma of the uterine cervix: tailoring the radicality |
| sigel_instance_filter | dkfz geomar wilbert ipn albert |
| source_archive | Blackwell Publishing Journal Backfiles 1879-2005 |
| timestamp | 2024-05-06T08:10:13.816Z |
| titel | Extended radical hysterectomy in early-stage carcinoma of the uterine cervix: tailoring the radicality |
| titel_suche | Extended radical hysterectomy in early-stage carcinoma of the uterine cervix: tailoring the radicality |
| topic | WW-YZ |
| uid | nat_lic_papers_NLZ239409779 |