A comparison of triazolam and diazepam as premedication agents for minor gynaecological surgery
PINNOCK, C. A. ; FELL, D. ; HUNT, P. C. W. ; MILLER, R. ; SMITH, G.
Oxford, UK : Blackwell Publishing Ltd
Published 1985
Oxford, UK : Blackwell Publishing Ltd
Published 1985
ISSN: |
1365-2044
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Source: |
Blackwell Publishing Journal Backfiles 1879-2005
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Topics: |
Medicine
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Notes: |
Triazolam 0.25 mg, diazepam 10 mg and placebo were compared in a randomized double-blind trial of oral premedication in 90 patients undergoing minor gynaecological surgery. Both triazolam and diazepam produced a significant sedative effect as measured by patient serf assessment linear analogue scales but only diazepam was more anxiolytic than placebo. Psychomotor performance assessed by the letter-search test at 3 and 6 hours after awakening showed a decrement in performance in patients receiving triazolam at 3 hours compared with the two other groups. Triazolam was shown to have a pronounced amnesic effect and whilst it might be used for premedication, its lack of anxiolysis coupled with a significant impairment of psychomotor performance at 3 hours after awakening, render the drug unsuitable for premedication in the short stay patient.
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Type of Medium: |
Electronic Resource
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URL: |