Study of folate in psoriasis: blood levels, intestinal absorption and cutaneous loss
TOURAINE, R. ; REVUZ, J. ; ZITTOUN, J. ; JARRET, J. ; TULLIEZ, M.
Oxford, UK : Blackwell Publishing Ltd
Published 1973
Oxford, UK : Blackwell Publishing Ltd
Published 1973
| ISSN: |
1365-2133
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|---|---|
| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
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| Topics: |
Medicine
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| Notes: |
Serum, red cell and squame folate content have been measured in fifty cases of psoriasis with extensive lesions. Reduced serum and red cell folate have been found in 44% of the patients. Folic acid absorption, studied in twenty-six patients, was impaired in four and significantly increased in all the others.Squame folate content has been found too low to explain the folate deficiency. Malabsorption is a possible hypothesis but it occurs too rarely (four cases). The most likely explanation of folate deficiency seems to be an increased utilization of folate by the skin epidermal cells as a result of the rapid turnover rate.The increased absorption found in most cases investigated could be a compensatory mechanism to equilibrate folate balance.
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| Type of Medium: |
Electronic Resource
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| URL: |