LIQUOR BILIRUBIN VALUES IN EARLY PREGNANCY

1471-0528

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Liquor bilirubin concentrations have been measured chemically and spectrophotometrically throughout normal pregnancy in 80 patients and in 30 patients with fetuses affected by rhesus incompatibility.A normal curve and confidence intervals for a single observation of Δ 450 mμ. have been calculated. Prognostic criteria may be applied to gestations earlier than 28 weeks by use of the normal Δ 450 mμ. curve and the curve designating the 0·5 per cent confidence limit.Accurate criteria for intrauterine transfusion cannot be derived from Δ 450 mμ. values before 23–24 weeks and at this stage of pregnancy emphasis should be placed on the obstetric history.

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