LOW URINARY OESTRIOL EXCRETION DURING PREGNANCY ASSOCIATED WITH PLACENTAL SULPHATASE DEFICIENCY OR CONGENITAL ADRENAL HYPOPLASIA
Fliecner, J. R. H. ; Schindler, Irene ; Brown, J. B.
Oxford, UK : Blackwell Publishing Ltd
Published 1972
Oxford, UK : Blackwell Publishing Ltd
Published 1972
| ISSN: |
1471-0528
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| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
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| Topics: |
Medicine
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| Notes: |
The clinical details and outcome of eight pregnancies associated with very low oestriol excretion are reported. Three cases were associated with congenital adrenal hypoplasia which was confirmed at autopsy. In the remaining five cases the infants showed no clinical evidence of adrenal insufficiency, and the two placentae which were examined from these pregnancies were found to be deficient in placental sulphatase activity. It is likely that in all five cases placental sulphatase deficiency was present. To date all the reported cases of placental sulphatase deficiency have been with male fetuses and the condition appears to be sex linked.
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| Type of Medium: |
Electronic Resource
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| URL: |