RED CELL ANTIBODIES DETECTED IN ANTENATAL TESTS ON RHESUS POSITIVE WOMEN IN SOUTH AND MID WALES, 1948–1978
| ISSN: |
1471-0528
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|---|---|
| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
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| Topics: |
Medicine
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| Notes: |
A total of 733 rhesus positive women with antibodies were found during antenatal screening of 380 790 pregnancies in South and Mid Wales over a 30-year-period. A steady increase was observed in the frequency of antibodies, particularly non-rhesus antibodies and the mothers concerned had a significantly increased history of previous blood transfusion. In 50 per cent of those with non-rhesus antibodies, transfusion was the only stimulus. Conversely, for the majority (61 per cent) of women with rhesus antibodies feto-maternal incompatibility was the sole apparent stimulus. No identifiable stimulus could be found in 25 per cent of women with anti-E and 13 per cent of those with anti-Kell. Compared to rhesus negative mothers with anti-D severe clinical haemolytic disease of the newborn was uncommon, but in 75 per cent of rhesus positive mothers with infants carrying the homologous antigen, there was some evidence of haemolytic disease. Anti-c̄ was much the worst in this respect with 19.4 per cent of infants needing transfusion. The probability of having an incompatible infant was much less for the mothers with non-rhesus antibodies (27.3 per cent) and of these infants only 5.7 per cent needed transfusion.
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| Type of Medium: |
Electronic Resource
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| URL: |
| _version_ | 1798289965845577729 |
|---|---|
| autor | Hardy, Joan Napier, J. A. F. |
| book_url | http://dx.doi.org/10.1111/j.1471-0528.1981.tb00948.x |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLZ238773574 |
| insertion_date | 2012-04-17 |
| issn | 1471-0528 |
| journal_name | BJOG |
| materialart | 1 |
| notes | A total of 733 rhesus positive women with antibodies were found during antenatal screening of 380 790 pregnancies in South and Mid Wales over a 30-year-period. A steady increase was observed in the frequency of antibodies, particularly non-rhesus antibodies and the mothers concerned had a significantly increased history of previous blood transfusion. In 50 per cent of those with non-rhesus antibodies, transfusion was the only stimulus. Conversely, for the majority (61 per cent) of women with rhesus antibodies feto-maternal incompatibility was the sole apparent stimulus. No identifiable stimulus could be found in 25 per cent of women with anti-E and 13 per cent of those with anti-Kell. Compared to rhesus negative mothers with anti-D severe clinical haemolytic disease of the newborn was uncommon, but in 75 per cent of rhesus positive mothers with infants carrying the homologous antigen, there was some evidence of haemolytic disease. Anti-c̄ was much the worst in this respect with 19.4 per cent of infants needing transfusion. The probability of having an incompatible infant was much less for the mothers with non-rhesus antibodies (27.3 per cent) and of these infants only 5.7 per cent needed transfusion. |
| package_name | Blackwell Publishing |
| publikationsjahr_anzeige | 1981 |
| publikationsjahr_facette | 1981 |
| publikationsjahr_intervall | 8019:1980-1984 |
| publikationsjahr_sort | 1981 |
| publikationsort | Oxford, UK |
| publisher | Blackwell Publishing Ltd |
| reference | 88 (1981), S. 0 |
| search_space | articles |
| shingle_author_1 | Hardy, Joan Napier, J. A. F. |
| shingle_author_2 | Hardy, Joan Napier, J. A. F. |
| shingle_author_3 | Hardy, Joan Napier, J. A. F. |
| shingle_author_4 | Hardy, Joan Napier, J. A. F. |
| shingle_catch_all_1 | Hardy, Joan Napier, J. A. F. RED CELL ANTIBODIES DETECTED IN ANTENATAL TESTS ON RHESUS POSITIVE WOMEN IN SOUTH AND MID WALES, 1948–1978 Blackwell Publishing Ltd A total of 733 rhesus positive women with antibodies were found during antenatal screening of 380 790 pregnancies in South and Mid Wales over a 30-year-period. A steady increase was observed in the frequency of antibodies, particularly non-rhesus antibodies and the mothers concerned had a significantly increased history of previous blood transfusion. In 50 per cent of those with non-rhesus antibodies, transfusion was the only stimulus. Conversely, for the majority (61 per cent) of women with rhesus antibodies feto-maternal incompatibility was the sole apparent stimulus. No identifiable stimulus could be found in 25 per cent of women with anti-E and 13 per cent of those with anti-Kell. Compared to rhesus negative mothers with anti-D severe clinical haemolytic disease of the newborn was uncommon, but in 75 per cent of rhesus positive mothers with infants carrying the homologous antigen, there was some evidence of haemolytic disease. Anti-c̄ was much the worst in this respect with 19.4 per cent of infants needing transfusion. The probability of having an incompatible infant was much less for the mothers with non-rhesus antibodies (27.3 per cent) and of these infants only 5.7 per cent needed transfusion. 1471-0528 14710528 |
| shingle_catch_all_2 | Hardy, Joan Napier, J. A. F. RED CELL ANTIBODIES DETECTED IN ANTENATAL TESTS ON RHESUS POSITIVE WOMEN IN SOUTH AND MID WALES, 1948–1978 Blackwell Publishing Ltd A total of 733 rhesus positive women with antibodies were found during antenatal screening of 380 790 pregnancies in South and Mid Wales over a 30-year-period. A steady increase was observed in the frequency of antibodies, particularly non-rhesus antibodies and the mothers concerned had a significantly increased history of previous blood transfusion. In 50 per cent of those with non-rhesus antibodies, transfusion was the only stimulus. Conversely, for the majority (61 per cent) of women with rhesus antibodies feto-maternal incompatibility was the sole apparent stimulus. No identifiable stimulus could be found in 25 per cent of women with anti-E and 13 per cent of those with anti-Kell. Compared to rhesus negative mothers with anti-D severe clinical haemolytic disease of the newborn was uncommon, but in 75 per cent of rhesus positive mothers with infants carrying the homologous antigen, there was some evidence of haemolytic disease. Anti-c̄ was much the worst in this respect with 19.4 per cent of infants needing transfusion. The probability of having an incompatible infant was much less for the mothers with non-rhesus antibodies (27.3 per cent) and of these infants only 5.7 per cent needed transfusion. 1471-0528 14710528 |
| shingle_catch_all_3 | Hardy, Joan Napier, J. A. F. RED CELL ANTIBODIES DETECTED IN ANTENATAL TESTS ON RHESUS POSITIVE WOMEN IN SOUTH AND MID WALES, 1948–1978 Blackwell Publishing Ltd A total of 733 rhesus positive women with antibodies were found during antenatal screening of 380 790 pregnancies in South and Mid Wales over a 30-year-period. A steady increase was observed in the frequency of antibodies, particularly non-rhesus antibodies and the mothers concerned had a significantly increased history of previous blood transfusion. In 50 per cent of those with non-rhesus antibodies, transfusion was the only stimulus. Conversely, for the majority (61 per cent) of women with rhesus antibodies feto-maternal incompatibility was the sole apparent stimulus. No identifiable stimulus could be found in 25 per cent of women with anti-E and 13 per cent of those with anti-Kell. Compared to rhesus negative mothers with anti-D severe clinical haemolytic disease of the newborn was uncommon, but in 75 per cent of rhesus positive mothers with infants carrying the homologous antigen, there was some evidence of haemolytic disease. Anti-c̄ was much the worst in this respect with 19.4 per cent of infants needing transfusion. The probability of having an incompatible infant was much less for the mothers with non-rhesus antibodies (27.3 per cent) and of these infants only 5.7 per cent needed transfusion. 1471-0528 14710528 |
| shingle_catch_all_4 | Hardy, Joan Napier, J. A. F. RED CELL ANTIBODIES DETECTED IN ANTENATAL TESTS ON RHESUS POSITIVE WOMEN IN SOUTH AND MID WALES, 1948–1978 Blackwell Publishing Ltd A total of 733 rhesus positive women with antibodies were found during antenatal screening of 380 790 pregnancies in South and Mid Wales over a 30-year-period. A steady increase was observed in the frequency of antibodies, particularly non-rhesus antibodies and the mothers concerned had a significantly increased history of previous blood transfusion. In 50 per cent of those with non-rhesus antibodies, transfusion was the only stimulus. Conversely, for the majority (61 per cent) of women with rhesus antibodies feto-maternal incompatibility was the sole apparent stimulus. No identifiable stimulus could be found in 25 per cent of women with anti-E and 13 per cent of those with anti-Kell. Compared to rhesus negative mothers with anti-D severe clinical haemolytic disease of the newborn was uncommon, but in 75 per cent of rhesus positive mothers with infants carrying the homologous antigen, there was some evidence of haemolytic disease. Anti-c̄ was much the worst in this respect with 19.4 per cent of infants needing transfusion. The probability of having an incompatible infant was much less for the mothers with non-rhesus antibodies (27.3 per cent) and of these infants only 5.7 per cent needed transfusion. 1471-0528 14710528 |
| shingle_title_1 | RED CELL ANTIBODIES DETECTED IN ANTENATAL TESTS ON RHESUS POSITIVE WOMEN IN SOUTH AND MID WALES, 1948–1978 |
| shingle_title_2 | RED CELL ANTIBODIES DETECTED IN ANTENATAL TESTS ON RHESUS POSITIVE WOMEN IN SOUTH AND MID WALES, 1948–1978 |
| shingle_title_3 | RED CELL ANTIBODIES DETECTED IN ANTENATAL TESTS ON RHESUS POSITIVE WOMEN IN SOUTH AND MID WALES, 1948–1978 |
| shingle_title_4 | RED CELL ANTIBODIES DETECTED IN ANTENATAL TESTS ON RHESUS POSITIVE WOMEN IN SOUTH AND MID WALES, 1948–1978 |
| sigel_instance_filter | dkfz geomar wilbert ipn albert |
| source_archive | Blackwell Publishing Journal Backfiles 1879-2005 |
| timestamp | 2024-05-06T08:09:13.810Z |
| titel | RED CELL ANTIBODIES DETECTED IN ANTENATAL TESTS ON RHESUS POSITIVE WOMEN IN SOUTH AND MID WALES, 1948–1978 |
| titel_suche | RED CELL ANTIBODIES DETECTED IN ANTENATAL TESTS ON RHESUS POSITIVE WOMEN IN SOUTH AND MID WALES, 1948–1978 |
| topic | WW-YZ |
| uid | nat_lic_papers_NLZ238773574 |