Fertility and pregnancy after operation for a prolactinoma

RICHARDS, AMANDA M. ; BULLOCK, M. R. R. ; TEASDALE, G. M. ; THOMSON, J. A. ; KHAN, M. I.

Oxford, UK : Blackwell Publishing Ltd
Published 1986
ISSN:
1471-0528
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Summary. Pituitary exploration was performed in 40 women with hyperprolactinaemic infertility and a prolactinoma was found in 37. After operation 26 (65%) of the 40 patients had a normal serum prolactin concentration; 31 women have so far had 49 pregnancies; in seven of these patients bromocriptine therapy was used after surgery. Eight of the remaining nine women were shown to be ovulating, but four of these subsequently decided not to attempt a pregnancy. The course and outcome of the 49 pregnancies were similar to those in normal women and no visual or endocrine complications occurred. Surgical removal of a prolactinoma often restores fertility, and may secure a safer pregnancy.
Type of Medium:
Electronic Resource
URL: