THE INFLUENCE OF A HIGH K INTAKE ON THE HYPERTENSIVE EFFECT OF ACTH AND DOC IN SHEEP
Mills, E. H. ; Coghlan, J. P. ; Denton, D. A. ; Scoggins, B. A. ; Spence, C. D. ; Whitworth, J. A.
Oxford, UK : Blackwell Publishing Ltd
Published 1983
Oxford, UK : Blackwell Publishing Ltd
Published 1983
| ISSN: |
1440-1681
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| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
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| Topics: |
Medicine
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| Notes: |
1. The effect of 5 days administration of ACTH or DOC, was examined before and after chronic potassium (K) loading in sheep.2. K loading raised plasma [K], urine volume and K excretion but had no effect on mean arterial pressure (MAP).3. On a normal K intake DOC (5 mg/day i.v.) increased MAP and plasma sodium [Na]. Plasma [K], urinary Na (day 1) and K (day 1) excretion were decreased. On a high K intake (≃800 mmol K/day), DOC lowered plasma [K] but had no effect on MAP or Na excretion.4. The hypertensive effects of ACTH were not affected by K intake.
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| Type of Medium: |
Electronic Resource
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| URL: |