Structural changes in glycogen phosphorylase induced by phosphorylation
Sprang, S. R. ; Acharya, K. R. ; Goldsmith, E. J. ; Stuart, D. I. ; Varvill, K. ; Fletterick, R. J. ; Madsen, N. B. ; Johnson, L. N.
[s.l.] : Nature Publishing Group
Published 1988
[s.l.] : Nature Publishing Group
Published 1988
ISSN: |
1476-4687
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Source: |
Nature Archives 1869 - 2009
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Topics: |
Biology
Chemistry and Pharmacology
Medicine
Natural Sciences in General
Physics
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Notes: |
[Auszug] A comparison of the refined crystal structures of dimeric glycogen phosphorylase b and a reveals structural changes that represent the first step in the activation of the enzyme. On phosphorylation of serine-14, the N-terminus of each subunit assumes an ordered helical conformation and binds to the ...
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Type of Medium: |
Electronic Resource
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URL: |