Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs
Hannum, C. ; Culpepper, J. ; Campbell, D. ; McClanahan, T. ; Zurawski, S. ; Kastelein, R. ; Bazan, J. F. ; Hudak, S. ; Wagner, J. ; Mattson, J. ; Luh, J. ; Duda, G. ; Martina, N. ; Peterson, D ; Menon, S. ; Shanafelt, A. ; Muench, M. ; Kelner, G. ; Namikawa, R. ; Rennick, D. ; Roncarolo, M.-G. ; Zlotnik, A. ; Rosnet, O. ; Dubreuil, P. ; Birnbaum, D.
[s.l.] : Nature Publishing Group
Published 1994
[s.l.] : Nature Publishing Group
Published 1994
ISSN: |
1476-4687
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Source: |
Nature Archives 1869 - 2009
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Topics: |
Biology
Chemistry and Pharmacology
Medicine
Natural Sciences in General
Physics
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Notes: |
[Auszug] To develop an assay for the FLT3/FLK2 ligand (FL) and to identify producer cells, we transfected the pro-B cell line Ba/F3 (ref. 6) with a cDNA clone encoding mouse FLT3/FLK2. Stable transformants, called Baflt, were then used as target cells in a proliferation assay with conditioned medium from ...
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Type of Medium: |
Electronic Resource
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URL: |