A potential catalytic site revealed by the 1.7-Å crystal structure of the amino-terminal signalling domain of Sonic hedgehog
Hall, Traci M. Tanaka ; Porter, Jeffery A. ; Beachy, Philip A. ; Leahy, Daniel J.
[s.l.] : Nature Publishing Group
Published 1995
[s.l.] : Nature Publishing Group
Published 1995
| ISSN: |
1476-4687
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| Source: |
Nature Archives 1869 - 2009
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| Topics: |
Biology
Chemistry and Pharmacology
Medicine
Natural Sciences in General
Physics
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| Notes: |
[Auszug] Crystals of both native and selenomethionyl-substituted (SeMet) Shh-N were grown, and the structure of SeMet Shh-Nwas determined by the multiwavelength anomalous diffraction (MAD) method10'1', as summarized in Table 1. The Shh-N structure consists of a core a 4- P sandwich of two a-helices ...
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| Type of Medium: |
Electronic Resource
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| URL: |