Dominant negative mutations in human PPARĪ³ associated with severe insulin resistance, diabetes mellitus and hypertension
Barroso, I. ; Gurnell, M. ; Crowley, V. E. F. ; Agostini, M. ; Schwabe, J. W. ; Soos, M. A. ; Maslen, G. LI ; Williams, T. D. M. ; Lewis, H. ; Schafer, A. J. ; Chatterjee, V. K. K. ; O'Rahilly, S.
[s.l.] : Macmillian Magazines Ltd.
Published 1999
[s.l.] : Macmillian Magazines Ltd.
Published 1999
| ISSN: |
1476-4687
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|---|---|
| Source: |
Nature Archives 1869 - 2009
|
| Topics: |
Biology
Chemistry and Pharmacology
Medicine
Natural Sciences in General
Physics
|
| Notes: |
[Auszug] Thiazolidinediones are a new class of antidiabetic agent that improve insulin sensitivity and reduce plasma glucose and blood pressure in subjects with type 2 diabetes. Although these agents can bind and activate an orphan nuclear receptor, peroxisome proliferator-activated receptor gamma ...
|
| Type of Medium: |
Electronic Resource
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| URL: |