A New Type of Cytotoxic Immunosuppressive Agent: 3-Acetyl-5-(4-fluorobenzylidene)4-hydroxy-2-oxo-2:5-dihydrothiophen

FRANKLIN, T. J. ; NEWBOULD, B. B. ; O'MANT, D. M. ; SCOTT, A. I. ; STACEY, G. J. ; DAVIES, G. E.

[s.l.] : Nature Publishing Group
Published 1966
ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
Chemistry and Pharmacology
Medicine
Natural Sciences in General
Physics
Notes:
[Auszug] This communication describes the properties of one of the more active compounds in the series, I.C.I. 47,776 (I, R = methyl, X = 4-fluoro), which may be prepared by condensation of 4-fluorobenzaldehyde with 3-acetyl-4-hydroxy-2-oxo-2 : 5-dihydrothiophen under either acidic or basic conditions3. It ...
Type of Medium:
Electronic Resource
URL: