2-(4-chlorophenyl)thiazol-4-ylacetic Acid (‘Myalex’): a New Compound with Anti-inflammatory, Analgesic and Antipyretic Activity

HEPWORTH, W. ; NEWBOULD, B. B. ; PLATT, D. S. ; STACEY, G. J.

[s.l.] : Nature Publishing Group
Published 1969
ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
Chemistry and Pharmacology
Medicine
Natural Sciences in General
Physics
Notes:
[Auszug] Our initial observation was that 25 mg/kg of ethyl 4-(4-bromophenyl)thiazol-2-ylacetate, ICI 52,722 (I), given by mouth daily, reduced the inflammation associated with the development of both "primary" and "secondary" lesions in rats with adjuvant-induced arthritis. Compound ICI 54,450, ...
Type of Medium:
Electronic Resource
URL: