Human pulmonary alveolar macrophages metabolise benzo( a )pyrene to proximate and ultimate mutagens

HARRIS, CURTIS C. ; Hsu, IH CHANG ; STONER, GARY D. ; TRUMP, BENJAMIN F. ; SELKIRK, JAMES K.

[s.l.] : Nature Publishing Group
Published 1978
ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
Chemistry and Pharmacology
Medicine
Natural Sciences in General
Physics
Notes:
[Auszug] For the detection of mutations, the cell-mediated mutagenesis system first described by Huberman and Sachs4 was modified by substituting, as the activating cell type, human PAM in place of Syrian golden hamster embryo cells. The indicator cells, Chinese hamster V-79 cells5, do not effectively ...
Type of Medium:
Electronic Resource
URL: