Sodium current depression by lidocaine and quinidine in isolated ventricular cells

Lee, K. S. ; Hume, J. R. ; Giles, W. ; Brown, A. M.

[s.l.] : Nature Publishing Group
Published 1981
ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
Chemistry and Pharmacology
Medicine
Natural Sciences in General
Physics
Notes:
[Auszug] Weidmann2 first reported that the local anaesthetic cocaine depresses the maximum upstroke velocity (V^ax) of the action potential in sheep Purkinje fibres; his results also suggested that this effect was produced by a voltage-dependent shift in the inactivation mechanism governing /Na. Johnson and ...
Type of Medium:
Electronic Resource
URL: