Mapping of a Protective Epitope of Pertussis Toxin by In Vitro Refolding of Recombinant Fragments
Bartoloni, A. ; Pizza, M. ; Bigio, M. ; Nucci, D. ; Ashworth, L. A. ; Irons, L. I. ; Robinson, A. ; Burns, D. ; Manclark, C. ; Sato, H. ; Rappuoli, R.
[s.l.] : Nature Publishing Company
Published 1988
[s.l.] : Nature Publishing Company
Published 1988
| ISSN: |
1546-1696
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|---|---|
| Source: |
Nature Archives 1869 - 2009
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| Topics: |
Biology
Process Engineering, Biotechnology, Nutrition Technology
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| Notes: |
[Auszug] Antigenic determinants are often composed of discontiguous polypeptide segments, adjacent on protein surfaces, which are difficult to map by conventional techniques. Here we show that although monoclonal antibodies did not recognize recombinant molecules containing only the aminoterminal or only ...
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| Type of Medium: |
Electronic Resource
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| URL: |