Genomic instability in Gadd45a- deficient mice
Hollander, M. Christine ; Sheikh, M. Saeed ; Bulavin, Dmitry V. ; Lundgren, Karen ; Augeri-Henmueller, Laura ; Shehee, Ronald ; Molinaro, Thomas A. ; Kim, Kate E. ; Tolosa, Eva ; Ashwell, Jonathan D. ; Rosenberg, Michael P. ; Zhan, Qimin ; Fernández-Salguero, Pedro M. ; Morgan, William F. ; Deng, Chu-Xia ; Fornace, Albert J.
[s.l.] : Nature America Inc.
Published 1999
[s.l.] : Nature America Inc.
Published 1999
ISSN: |
1546-1718
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Source: |
Nature Archives 1869 - 2009
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Topics: |
Biology
Medicine
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Notes: |
[Auszug] Gadd45a-null mice generated by gene targeting exhibited several of the phenotypes characteristic of p53-deficient mice, including genomic instability, increased radiation carcinogenesis and a low frequency of exencephaly. Genomic instability was exemplified by aneuploidy, chromosome ...
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Type of Medium: |
Electronic Resource
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URL: |