Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass
Chen, Airu S. ; Marsh, Donald J. ; Trumbauer, Myrna E. ; Frazier, Easter G. ; Guan, Xiao-Ming ; Yu, Hong ; Rosenblum, Charles I. ; Vongs, Aurawan ; Feng, Yue ; Cao, Linhai ; Metzger, Joseph M. ; Strack, Alison M. ; Camacho, Ramon E. ; Mellin, Theodore N. ; Nunes, Christian N. ; Min, William ; Fisher, Jill ; Gopal-Truter, Shobhna ; MacIntyre, D. Euan ; Chen, Howard Y. ; Van der Ploeg, Lex H.T.
[s.l.] : Nature America Inc.
Published 2000
[s.l.] : Nature America Inc.
Published 2000
| ISSN: |
1546-1718
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|---|---|
| Source: |
Nature Archives 1869 - 2009
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| Topics: |
Biology
Medicine
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| Notes: |
[Auszug] Genetic and pharmacological studies have defined a role for the melanocortin-4 receptor (Mc4r) in the regulation of energy homeostasis. The physiological function of Mc3r, a melanocortin receptor expressed at high levels in the hypothalamus, has remained unknown. We evaluated the potential ...
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| Type of Medium: |
Electronic Resource
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| URL: |