Characterizing gene expression profile of Inv(16)-associated leukemia
Adya, N. ; Chen, Y. ; Hilgenfeld, E. ; Khan, J. ; Bittner, M. ; Serve, H. ; Berdel, W.E. ; Meltzer, P. ; Liu, P.P.
[s.l.] : Nature Publishing Group
Published 2001
[s.l.] : Nature Publishing Group
Published 2001
| ISSN: |
1546-1718
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| Source: |
Nature Archives 1869 - 2009
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| Topics: |
Biology
Medicine
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| Notes: |
[Auszug] Inversion 16 (Inv(16)) results in a fusion between genes CBFB on the q arm and MYH11 on the p arm and is associated with acute myeloid leukemia (AML) subtype M4Eo. CBFB encodes a protein (CBFb) that forms a heterodimeric transcription factor with RUNX1/AML1, which itself is disrupted by several ...
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| Type of Medium: |
Electronic Resource
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| URL: |