A mutation in Sec15l1 causes anemia in hemoglobin deficit ( hbd ) mice
Lim, Jackie E ; Jin, Ou ; Bennett, Carolyn ; Morgan, Kelly ; Wang, Fudi ; Trenor, Cameron C ; Fleming, Mark D ; Andrews, Nancy C
[s.l.] : Nature Publishing Group
Published 2005
[s.l.] : Nature Publishing Group
Published 2005
| ISSN: |
1546-1718
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| Source: |
Nature Archives 1869 - 2009
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| Topics: |
Biology
Medicine
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| Notes: |
[Auszug] Hemoglobin deficit (hbd) mice carry a spontaneous mutation that impairs erythroid iron assimilation but does not cause other defects. Normal delivery of iron to developing erythroid precursors is highly dependent on the transferrin cycle. Through genetic mapping and complementation experiments, we ...
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| Type of Medium: |
Electronic Resource
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| URL: |