Analysis of the p16 gene ( CDKN2 ) as a candidate for the chromosome 9p melanoma susceptibility locus

ISSN:
1546-1718
Source:
Nature Archives 1869 - 2009
Topics:
Biology
Medicine
Notes:
[Auszug] A locus for familial melanoma, MLM, has been mapped within the same interval on chromosome 9p21 as the gene for a putative cell cycle regulator, p16INK4 (CDKN2) MTS1. This gene is homozygously deleted from many tumour cell lines including melanomas, suggesting that CDKN2 is a good candidate for ...
Type of Medium:
Electronic Resource
URL: