Analysis of the p16 gene ( CDKN2 ) as a candidate for the chromosome 9p melanoma susceptibility locus
Kamb, A. ; Shattuck-Eidens, D. ; Eeles, R. ; Liu, Q. ; Gruis, N. A. ; Ding, W. ; Hussey, C. ; Tran, T. ; Miki, Y. ; Weaver-Feldhaus, J. ; McClure, M. ; Aitken, J. F. ; Anderson, D. E. ; Bergman, W. ; Frants, R. ; Goldgar, D. E. ; Green, A. ; MacLennan, R. ; Martin, N. G. ; Meyer, L. J. ; Youl, P. ; Zone, J. J. ; Skolnick, M. H. ; Cannon-Albright, L. A.
[s.l.] : Nature Publishing Group
Published 1994
[s.l.] : Nature Publishing Group
Published 1994
ISSN: |
1546-1718
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Source: |
Nature Archives 1869 - 2009
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Topics: |
Biology
Medicine
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Notes: |
[Auszug] A locus for familial melanoma, MLM, has been mapped within the same interval on chromosome 9p21 as the gene for a putative cell cycle regulator, p16INK4 (CDKN2) MTS1. This gene is homozygously deleted from many tumour cell lines including melanomas, suggesting that CDKN2 is a good candidate for ...
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Type of Medium: |
Electronic Resource
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URL: |