Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation
Korn, Thomas ; Reddy, Jayagopala ; Gao, Wenda ; Bettelli, Estelle ; Awasthi, Amit ; Petersen, Troels R ; Bäckström, B Thomas ; Sobel, Raymond A ; Wucherpfennig, Kai W ; Strom, Terry B ; Oukka, Mohamed ; Kuchroo, Vijay K
[s.l.] : Nature Publishing Group
Published 2007
[s.l.] : Nature Publishing Group
Published 2007
| ISSN: |
1546-170X
|
|---|---|
| Source: |
Nature Archives 1869 - 2009
|
| Topics: |
Biology
Medicine
|
| Notes: |
[Auszug] Treatment with ex vivo–generated regulatory T cells (T-reg) has been regarded as a potentially attractive therapeutic approach for autoimmune diseases. However, the dynamics and function of T-reg in autoimmunity are not well understood. Thus, we developed Foxp3gfp knock-in (Foxp3gfp.KI) mice ...
|
| Type of Medium: |
Electronic Resource
|
| URL: |