Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families
Tonin, P. ; Weber, B. ; Offit, K. ; Couch, F. ; Rebbeck, T.R. ; Neuhausen, S. ; Godwin, A.K. ; Daly, M. ; Wagner-Costalos, J. ; Berman, D. ; Grana, G. ; Fox, E. ; Kane, M.F. ; Kolodner, R.D. ; Krainer, M. ; Haber, D.A. ; Struewing, J.P. ; Warner, E. ; Rosen, B. ; Lerman, C. ; Peshkin, B. ; Norton, L. ; Serova, O. ; Foulkes, W.D. ; Lynch, H.T.
[s.l.] : Nature Publishing Group
Published 1996
[s.l.] : Nature Publishing Group
Published 1996
| ISSN: |
1546-170X
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|---|---|
| Source: |
Nature Archives 1869 - 2009
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| Topics: |
Biology
Medicine
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| Notes: |
[Auszug] Germline mutations in the breast cancer susceptibility genes BRCA1 and BRCA2 account for the majority of families with hereditary breast cancer. Among women with BRCA1 mutations, the lifetime risk of breast cancer exceeds 80%, and the risk of ovarian cancer approaches 50% (ref. 1). ...
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| Type of Medium: |
Electronic Resource
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| URL: |