Sequence and structure of the mouse gene coding for the largest neurofilament subunit
Julien, J.-P. ; Cote, F. ; Beaudet, L. ; Sidky, M. ; Flavell, D. ; Grosveld, F. ; Mushynski, W.
Amsterdam : Elsevier
Amsterdam : Elsevier
| ISSN: |
0378-1119
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|---|---|
| Keywords: |
CpG-rich island ; Intermediate filament ; intron positions ; neuron-specific gene ; phosphorylation site ; recombinant DNA
|
| Source: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
|
| Topics: |
Biology
|
| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798292005202165760 |
|---|---|
| autor | Julien, J.-P. Cote, F. Beaudet, L. Sidky, M. Flavell, D. Grosveld, F. Mushynski, W. |
| autorsonst | Julien, J.-P. Cote, F. Beaudet, L. Sidky, M. Flavell, D. Grosveld, F. Mushynski, W. |
| book_url | http://linkinghub.elsevier.com/retrieve/pii/0378-1119(88)90033-9 |
| datenlieferant | nat_lic_papers |
| fussnote | We have determined the complete nucleotide sequence of the mouse gene encoding the neurofilament NF-H protein. The C-terminal domain of NF-H is very rich in charged amino acids (aa) and contains a 3-aa sequence, Lys-Ser-Pro, that is repeated 51 times within a stretch of 368 aa. The location of this serine-rich repeat in the phosphorylated domain of NF-H indicates that it represents the major protein kinase recognition site. The nfh gene shares two common intron positions with the nfl and nfm genes, but has an additional intron that occurs at a location equivalent to one of the introns in non-neuronal intermediate filament-coding genes. This additional nfh intron may have been acquired via duplication of a primordial intermediate filament gene. |
| hauptsatz | hsatz_simple |
| identnr | NLZ187354367 |
| issn | 0378-1119 |
| journal_name | Gene |
| materialart | 1 |
| package_name | Elsevier |
| publikationsort | Amsterdam |
| publisher | Elsevier |
| reference | 68 (1988), S. 307-314 |
| schlagwort | CpG-rich island Intermediate filament intron positions neuron-specific gene phosphorylation site recombinant DNA |
| search_space | articles |
| shingle_author_1 | Julien, J.-P. Cote, F. Beaudet, L. Sidky, M. Flavell, D. Grosveld, F. Mushynski, W. |
| shingle_author_2 | Julien, J.-P. Cote, F. Beaudet, L. Sidky, M. Flavell, D. Grosveld, F. Mushynski, W. |
| shingle_author_3 | Julien, J.-P. Cote, F. Beaudet, L. Sidky, M. Flavell, D. Grosveld, F. Mushynski, W. |
| shingle_author_4 | Julien, J.-P. Cote, F. Beaudet, L. Sidky, M. Flavell, D. Grosveld, F. Mushynski, W. |
| shingle_catch_all_1 | Julien, J.-P. Cote, F. Beaudet, L. Sidky, M. Flavell, D. Grosveld, F. Mushynski, W. Sequence and structure of the mouse gene coding for the largest neurofilament subunit CpG-rich island Intermediate filament intron positions neuron-specific gene phosphorylation site recombinant DNA CpG-rich island Intermediate filament intron positions neuron-specific gene phosphorylation site recombinant DNA 0378-1119 03781119 Elsevier |
| shingle_catch_all_2 | Julien, J.-P. Cote, F. Beaudet, L. Sidky, M. Flavell, D. Grosveld, F. Mushynski, W. Sequence and structure of the mouse gene coding for the largest neurofilament subunit CpG-rich island Intermediate filament intron positions neuron-specific gene phosphorylation site recombinant DNA CpG-rich island Intermediate filament intron positions neuron-specific gene phosphorylation site recombinant DNA 0378-1119 03781119 Elsevier |
| shingle_catch_all_3 | Julien, J.-P. Cote, F. Beaudet, L. Sidky, M. Flavell, D. Grosveld, F. Mushynski, W. Sequence and structure of the mouse gene coding for the largest neurofilament subunit CpG-rich island Intermediate filament intron positions neuron-specific gene phosphorylation site recombinant DNA CpG-rich island Intermediate filament intron positions neuron-specific gene phosphorylation site recombinant DNA 0378-1119 03781119 Elsevier |
| shingle_catch_all_4 | Julien, J.-P. Cote, F. Beaudet, L. Sidky, M. Flavell, D. Grosveld, F. Mushynski, W. Sequence and structure of the mouse gene coding for the largest neurofilament subunit CpG-rich island Intermediate filament intron positions neuron-specific gene phosphorylation site recombinant DNA CpG-rich island Intermediate filament intron positions neuron-specific gene phosphorylation site recombinant DNA 0378-1119 03781119 Elsevier |
| shingle_title_1 | Sequence and structure of the mouse gene coding for the largest neurofilament subunit |
| shingle_title_2 | Sequence and structure of the mouse gene coding for the largest neurofilament subunit |
| shingle_title_3 | Sequence and structure of the mouse gene coding for the largest neurofilament subunit |
| shingle_title_4 | Sequence and structure of the mouse gene coding for the largest neurofilament subunit |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
| timestamp | 2024-05-06T08:41:38.237Z |
| titel | Sequence and structure of the mouse gene coding for the largest neurofilament subunit |
| titel_suche | Sequence and structure of the mouse gene coding for the largest neurofilament subunit We have determined the complete nucleotide sequence of the mouse gene encoding the neurofilament NF-H protein. The C-terminal domain of NF-H is very rich in charged amino acids (aa) and contains a 3-aa sequence, Lys-Ser-Pro, that is repeated 51 times within a stretch of 368 aa. The location of this serine-rich repeat in the phosphorylated domain of NF-H indicates that it represents the major protein kinase recognition site. The nfh gene shares two common intron positions with the nfl and nfm genes, but has an additional intron that occurs at a location equivalent to one of the introns in non-neuronal intermediate filament-coding genes. This additional nfh intron may have been acquired via duplication of a primordial intermediate filament gene. |
| topic | W |
| uid | nat_lic_papers_NLZ187354367 |