Immunocytochemical localisation of GABA in endocrine cells of the rat entero-pancreatic system
| ISSN: |
0248-4900
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|---|---|
| Keywords: |
GABA ; duodenum ; endocrine cells ; immunocytochemistry ; pancreas
|
| Source: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
|
| Topics: |
Biology
|
| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798291724646219777 |
|---|---|
| autor | Gilon, P. Campistron, G. Geffard, M. Remacle, C. |
| autorsonst | Gilon, P. Campistron, G. Geffard, M. Remacle, C. |
| book_url | http://linkinghub.elsevier.com/retrieve/pii/0248-4900(88)90021-4 |
| datenlieferant | nat_lic_papers |
| fussnote | The occurence of GABA-containing cells in the rat entero-pancreatic system was investigated by using anti-GABA-glutaraldehyde antibodies at the light and electron microscope level. In the pancreas, the B cells showed intense immunoreactivity, contrary to non-B and exocrine cells. Moreover, post-embedding immunogold staining was localised mostly in mitochondria, close to rough endoplasmic reticulum and in the nucleus. The insulin granules appeared non-significantly stained, which suggests the lack of cosecretion of GABA together with insulin. In the duodenum, GABA immunoreactivity was detected in certain endocrine cell types, suggesting a possible interaction with this amino acid. The well established GABAergic innervation in the enteric system was also confirmed by immunolabelling. |
| hauptsatz | hsatz_simple |
| identnr | NLZ18694442X |
| issn | 0248-4900 |
| journal_name | Biology of the Cell |
| materialart | 1 |
| package_name | Elsevier |
| publikationsort | Amsterdam |
| publisher | Elsevier |
| reference | 62 (1988), S. 265-273 |
| schlagwort | GABA duodenum endocrine cells immunocytochemistry pancreas |
| search_space | articles |
| shingle_author_1 | Gilon, P. Campistron, G. Geffard, M. Remacle, C. |
| shingle_author_2 | Gilon, P. Campistron, G. Geffard, M. Remacle, C. |
| shingle_author_3 | Gilon, P. Campistron, G. Geffard, M. Remacle, C. |
| shingle_author_4 | Gilon, P. Campistron, G. Geffard, M. Remacle, C. |
| shingle_catch_all_1 | Gilon, P. Campistron, G. Geffard, M. Remacle, C. Immunocytochemical localisation of GABA in endocrine cells of the rat entero-pancreatic system GABA duodenum endocrine cells immunocytochemistry pancreas GABA duodenum endocrine cells immunocytochemistry pancreas 0248-4900 02484900 Elsevier |
| shingle_catch_all_2 | Gilon, P. Campistron, G. Geffard, M. Remacle, C. Immunocytochemical localisation of GABA in endocrine cells of the rat entero-pancreatic system GABA duodenum endocrine cells immunocytochemistry pancreas GABA duodenum endocrine cells immunocytochemistry pancreas 0248-4900 02484900 Elsevier |
| shingle_catch_all_3 | Gilon, P. Campistron, G. Geffard, M. Remacle, C. Immunocytochemical localisation of GABA in endocrine cells of the rat entero-pancreatic system GABA duodenum endocrine cells immunocytochemistry pancreas GABA duodenum endocrine cells immunocytochemistry pancreas 0248-4900 02484900 Elsevier |
| shingle_catch_all_4 | Gilon, P. Campistron, G. Geffard, M. Remacle, C. Immunocytochemical localisation of GABA in endocrine cells of the rat entero-pancreatic system GABA duodenum endocrine cells immunocytochemistry pancreas GABA duodenum endocrine cells immunocytochemistry pancreas 0248-4900 02484900 Elsevier |
| shingle_title_1 | Immunocytochemical localisation of GABA in endocrine cells of the rat entero-pancreatic system |
| shingle_title_2 | Immunocytochemical localisation of GABA in endocrine cells of the rat entero-pancreatic system |
| shingle_title_3 | Immunocytochemical localisation of GABA in endocrine cells of the rat entero-pancreatic system |
| shingle_title_4 | Immunocytochemical localisation of GABA in endocrine cells of the rat entero-pancreatic system |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
| timestamp | 2024-05-06T08:37:11.152Z |
| titel | Immunocytochemical localisation of GABA in endocrine cells of the rat entero-pancreatic system |
| titel_suche | Immunocytochemical localisation of GABA in endocrine cells of the rat entero-pancreatic system The occurence of GABA-containing cells in the rat entero-pancreatic system was investigated by using anti-GABA-glutaraldehyde antibodies at the light and electron microscope level. In the pancreas, the B cells showed intense immunoreactivity, contrary to non-B and exocrine cells. Moreover, post-embedding immunogold staining was localised mostly in mitochondria, close to rough endoplasmic reticulum and in the nucleus. The insulin granules appeared non-significantly stained, which suggests the lack of cosecretion of GABA together with insulin. In the duodenum, GABA immunoreactivity was detected in certain endocrine cell types, suggesting a possible interaction with this amino acid. The well established GABAergic innervation in the enteric system was also confirmed by immunolabelling. |
| topic | W |
| uid | nat_lic_papers_NLZ18694442X |