Deletion 7q22 in uterine leiomyoma - A cytogenetic review

Ozisik, Y.Y. ; Meloni, A.M. ; Surti, U. ; Sandberg, A.A.

Amsterdam : Elsevier
ISSN:
0165-4608
Source:
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:
Medicine
Type of Medium:
Electronic Resource
URL:
_version_ 1798291600228483073
autor Ozisik, Y.Y.
Meloni, A.M.
Surti, U.
Sandberg, A.A.
autorsonst Ozisik, Y.Y.
Meloni, A.M.
Surti, U.
Sandberg, A.A.
book_url http://linkinghub.elsevier.com/retrieve/pii/0165-4608(93)90195-R
datenlieferant nat_lic_papers
fussnote The cytogenetic patterns of uterine leiomyomas have been extensively investigated, and cases characterized by specific clonal changes have been documented in detail. In these tumors one of the cytogenetic changes frequently observed has been a del(7), particularly del(7)(q22), usually as a sole anomaly. This is confirmed by our experience and by reports in the literature. The fact that del(7) is one of the most common abnormalities in leiomyoma raises the question of its role in tumor development. The main purpose of this review is to analyze the above aspect and to interpret its possible meaning. Our findings on cytogenetic abnormalities of chromosome 7 in leiomyoma, together with those reported in the literature, are reviewed and discussed. A listing of the genes located at 7q22 is also presented.
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identnr NLZ186743378
issn 0165-4608
journal_name Cancer Genetics and Cytogenetics
materialart 1
package_name Elsevier
publikationsort Amsterdam
publisher Elsevier
reference 71 (1993), S. 1-6
search_space articles
shingle_author_1 Ozisik, Y.Y.
Meloni, A.M.
Surti, U.
Sandberg, A.A.
shingle_author_2 Ozisik, Y.Y.
Meloni, A.M.
Surti, U.
Sandberg, A.A.
shingle_author_3 Ozisik, Y.Y.
Meloni, A.M.
Surti, U.
Sandberg, A.A.
shingle_author_4 Ozisik, Y.Y.
Meloni, A.M.
Surti, U.
Sandberg, A.A.
shingle_catch_all_1 Ozisik, Y.Y.
Meloni, A.M.
Surti, U.
Sandberg, A.A.
Deletion 7q22 in uterine leiomyoma - A cytogenetic review
0165-4608
01654608
Elsevier
shingle_catch_all_2 Ozisik, Y.Y.
Meloni, A.M.
Surti, U.
Sandberg, A.A.
Deletion 7q22 in uterine leiomyoma - A cytogenetic review
0165-4608
01654608
Elsevier
shingle_catch_all_3 Ozisik, Y.Y.
Meloni, A.M.
Surti, U.
Sandberg, A.A.
Deletion 7q22 in uterine leiomyoma - A cytogenetic review
0165-4608
01654608
Elsevier
shingle_catch_all_4 Ozisik, Y.Y.
Meloni, A.M.
Surti, U.
Sandberg, A.A.
Deletion 7q22 in uterine leiomyoma - A cytogenetic review
0165-4608
01654608
Elsevier
shingle_title_1 Deletion 7q22 in uterine leiomyoma - A cytogenetic review
shingle_title_2 Deletion 7q22 in uterine leiomyoma - A cytogenetic review
shingle_title_3 Deletion 7q22 in uterine leiomyoma - A cytogenetic review
shingle_title_4 Deletion 7q22 in uterine leiomyoma - A cytogenetic review
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source_archive Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
timestamp 2024-05-06T08:35:12.414Z
titel Deletion 7q22 in uterine leiomyoma - A cytogenetic review
titel_suche Deletion 7q22 in uterine leiomyoma - A cytogenetic review
The cytogenetic patterns of uterine leiomyomas have been extensively investigated, and cases characterized by specific clonal changes have been documented in detail. In these tumors one of the cytogenetic changes frequently observed has been a del(7), particularly del(7)(q22), usually as a sole anomaly. This is confirmed by our experience and by reports in the literature. The fact that del(7) is one of the most common abnormalities in leiomyoma raises the question of its role in tumor development. The main purpose of this review is to analyze the above aspect and to interpret its possible meaning. Our findings on cytogenetic abnormalities of chromosome 7 in leiomyoma, together with those reported in the literature, are reviewed and discussed. A listing of the genes located at 7q22 is also presented.
topic WW-YZ
uid nat_lic_papers_NLZ186743378