Metabolic engineering
| ISSN: |
0958-1669
|
|---|---|
| Keywords: |
FCC; flux control coefficient ; MCA; Metabolic Control Analysis ; NMR; nuclear magnetic resonance
|
| Source: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
|
| Topics: |
Medicine
Process Engineering, Biotechnology, Nutrition Technology
|
| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798292131792551936 |
|---|---|
| autor | Stephanopoulos, G. |
| autorsonst | Stephanopoulos, G. |
| book_url | http://dx.doi.org/10.1016/S0958-1669(05)80036-9 |
| datenlieferant | nat_lic_papers |
| fussnote | Metabolic engineering is not another form of classic manipulation of intermediary metabolism; rather, it is the purposeful design of metabolic networks. The metabolic engineering approach examines biochemical reactions in their entirety, rather than individually, and is concerned with the construction of novel pathways, the thermodynamic feasibility of pathways, and the location of limiting branch-point(s) and enzymatic reaction(s) in a reaction network. The ultimate goal is the construction of strains with superior yield and productivity obtained through a convergent evolutionary process. Progress has been made toward this objective within the framework of Metabolic Control Analysis through the development of methodologies for the experimental determination of elasticities and flux control coefficients. |
| hauptsatz | hsatz_simple |
| identnr | NLZ18520614X |
| iqvoc_descriptor_keyword | iqvoc_00000708:Analysis |
| issn | 0958-1669 |
| journal_name | Current Opinion in Biotechnology |
| materialart | 1 |
| package_name | Elsevier |
| publikationsort | Amsterdam |
| publisher | Elsevier |
| reference | 5 (1994), S. 196-200 |
| schlagwort | FCC; flux control coefficient MCA; Metabolic Control Analysis NMR; nuclear magnetic resonance |
| search_space | articles |
| shingle_author_1 | Stephanopoulos, G. |
| shingle_author_2 | Stephanopoulos, G. |
| shingle_author_3 | Stephanopoulos, G. |
| shingle_author_4 | Stephanopoulos, G. |
| shingle_catch_all_1 | Stephanopoulos, G. Metabolic engineering FCC; flux control coefficient MCA; Metabolic Control Analysis NMR; nuclear magnetic resonance FCC; flux control coefficient MCA; Metabolic Control Analysis NMR; nuclear magnetic resonance 0958-1669 09581669 Elsevier |
| shingle_catch_all_2 | Stephanopoulos, G. Metabolic engineering FCC; flux control coefficient MCA; Metabolic Control Analysis NMR; nuclear magnetic resonance FCC; flux control coefficient MCA; Metabolic Control Analysis NMR; nuclear magnetic resonance 0958-1669 09581669 Elsevier |
| shingle_catch_all_3 | Stephanopoulos, G. Metabolic engineering FCC; flux control coefficient MCA; Metabolic Control Analysis NMR; nuclear magnetic resonance FCC; flux control coefficient MCA; Metabolic Control Analysis NMR; nuclear magnetic resonance 0958-1669 09581669 Elsevier |
| shingle_catch_all_4 | Stephanopoulos, G. Metabolic engineering FCC; flux control coefficient MCA; Metabolic Control Analysis NMR; nuclear magnetic resonance FCC; flux control coefficient MCA; Metabolic Control Analysis NMR; nuclear magnetic resonance 0958-1669 09581669 Elsevier |
| shingle_title_1 | Metabolic engineering |
| shingle_title_2 | Metabolic engineering |
| shingle_title_3 | Metabolic engineering |
| shingle_title_4 | Metabolic engineering |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
| timestamp | 2024-05-06T08:43:39.344Z |
| titel | Metabolic engineering |
| titel_suche | Metabolic engineering Metabolic engineering is not another form of classic manipulation of intermediary metabolism; rather, it is the purposeful design of metabolic networks. The metabolic engineering approach examines biochemical reactions in their entirety, rather than individually, and is concerned with the construction of novel pathways, the thermodynamic feasibility of pathways, and the location of limiting branch-point(s) and enzymatic reaction(s) in a reaction network. The ultimate goal is the construction of strains with superior yield and productivity obtained through a convergent evolutionary process. Progress has been made toward this objective within the framework of Metabolic Control Analysis through the development of methodologies for the experimental determination of elasticities and flux control coefficients. |
| topic | WW-YZ ZM |
| uid | nat_lic_papers_NLZ18520614X |