Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome
Chen, E.Y. ; Cheng, A. ; Lee, A. ; Kuang, W.-J. ; Hillier, L. ; Green, P. ; Schlessinger, D. ; Ciccodicola, A. ; D'Urso, M.
Amsterdam : Elsevier
Amsterdam : Elsevier
| ISSN: |
0888-7543
|
|---|---|
| Source: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
|
| Topics: |
Biology
Medicine
|
| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798292085545107457 |
|---|---|
| autor | Chen, E.Y. Cheng, A. Lee, A. Kuang, W.-J. Hillier, L. Green, P. Schlessinger, D. Ciccodicola, A. D'Urso, M. |
| autorsonst | Chen, E.Y. Cheng, A. Lee, A. Kuang, W.-J. Hillier, L. Green, P. Schlessinger, D. Ciccodicola, A. D'Urso, M. |
| book_url | http://dx.doi.org/10.1016/0888-7543(91)90465-Q |
| datenlieferant | nat_lic_papers |
| fussnote | The sequence of 20,114 bp of DNA including the human glucose-6-phosphate dehydrogenase (G6PD) gene was determined. The region included a prominent CpG island, starting about 680 nucleotides upstream of the transcription start site, extending about 1050 nucleotides downstream of the start site, and ending just at the start of the first intron. The transcribed region from the start site to the poly (A) addition site covers 15,860 bp. The sequence of the 13 exons agreed with published cDNA sequence and for the 11 exons tested, with the corresponding sequence in a yeast artificial chromosome (YAC). The latter confirms YAC cloning fidelity at the DNA sequence level. Sixteen Alu sequences constitute 24% of the total sequence tract. Four were outside the borders of the mRNA transcript of the gene; all the others were found in a large (9858 bp) intron between exons 2 and 3. Two Alu clusters each contain Alus lying between the monomers of another. |
| hauptsatz | hsatz_simple |
| identnr | NLZ18441010X |
| issn | 0888-7543 |
| journal_name | Genomics |
| materialart | 1 |
| package_name | Elsevier |
| publikationsort | Amsterdam |
| publisher | Elsevier |
| reference | 10 (1991), S. 792-800 |
| search_space | articles |
| shingle_author_1 | Chen, E.Y. Cheng, A. Lee, A. Kuang, W.-J. Hillier, L. Green, P. Schlessinger, D. Ciccodicola, A. D'Urso, M. |
| shingle_author_2 | Chen, E.Y. Cheng, A. Lee, A. Kuang, W.-J. Hillier, L. Green, P. Schlessinger, D. Ciccodicola, A. D'Urso, M. |
| shingle_author_3 | Chen, E.Y. Cheng, A. Lee, A. Kuang, W.-J. Hillier, L. Green, P. Schlessinger, D. Ciccodicola, A. D'Urso, M. |
| shingle_author_4 | Chen, E.Y. Cheng, A. Lee, A. Kuang, W.-J. Hillier, L. Green, P. Schlessinger, D. Ciccodicola, A. D'Urso, M. |
| shingle_catch_all_1 | Chen, E.Y. Cheng, A. Lee, A. Kuang, W.-J. Hillier, L. Green, P. Schlessinger, D. Ciccodicola, A. D'Urso, M. Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome 0888-7543 08887543 Elsevier |
| shingle_catch_all_2 | Chen, E.Y. Cheng, A. Lee, A. Kuang, W.-J. Hillier, L. Green, P. Schlessinger, D. Ciccodicola, A. D'Urso, M. Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome 0888-7543 08887543 Elsevier |
| shingle_catch_all_3 | Chen, E.Y. Cheng, A. Lee, A. Kuang, W.-J. Hillier, L. Green, P. Schlessinger, D. Ciccodicola, A. D'Urso, M. Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome 0888-7543 08887543 Elsevier |
| shingle_catch_all_4 | Chen, E.Y. Cheng, A. Lee, A. Kuang, W.-J. Hillier, L. Green, P. Schlessinger, D. Ciccodicola, A. D'Urso, M. Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome 0888-7543 08887543 Elsevier |
| shingle_title_1 | Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome |
| shingle_title_2 | Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome |
| shingle_title_3 | Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome |
| shingle_title_4 | Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
| timestamp | 2024-05-06T08:42:54.371Z |
| titel | Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome |
| titel_suche | Sequence of human glucose-6-phosphate dehydrogenase cloned in plasmids and a yeast artificial chromosome The sequence of 20,114 bp of DNA including the human glucose-6-phosphate dehydrogenase (G6PD) gene was determined. The region included a prominent CpG island, starting about 680 nucleotides upstream of the transcription start site, extending about 1050 nucleotides downstream of the start site, and ending just at the start of the first intron. The transcribed region from the start site to the poly (A) addition site covers 15,860 bp. The sequence of the 13 exons agreed with published cDNA sequence and for the 11 exons tested, with the corresponding sequence in a yeast artificial chromosome (YAC). The latter confirms YAC cloning fidelity at the DNA sequence level. Sixteen Alu sequences constitute 24% of the total sequence tract. Four were outside the borders of the mRNA transcript of the gene; all the others were found in a large (9858 bp) intron between exons 2 and 3. Two Alu clusters each contain Alus lying between the monomers of another. |
| topic | W WW-YZ |
| uid | nat_lic_papers_NLZ18441010X |