Cellular recognition by rat liver cells of neuraminidase-treated erythrocytes - Demonstration and analysis of cell contacts

Kolb, H. ; Schudt, C. ; Kolb-Bachofen, V. ; Kolb, H.-A.

Amsterdam : Elsevier
ISSN:
0014-4827
Source:
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:
Biology
Medicine
Type of Medium:
Electronic Resource
URL:
_version_ 1798290796040945664
autor Kolb, H.
Schudt, C.
Kolb-Bachofen, V.
Kolb, H.-A.
autorsonst Kolb, H.
Schudt, C.
Kolb-Bachofen, V.
Kolb, H.-A.
book_url http://dx.doi.org/10.1016/0014-4827(78)90372-5
datenlieferant nat_lic_papers
fussnote Freshly isolated rat liver cells adhere firmly to neuraminidase-treated rat or mouse erythrocytes but not to untreated erythrocytes. Binding between cells occurs only in the presence of calcium and is specially inhibited by d-galactose. We therefore suggest that cell adherence is mediated by a galactose-specific hepatic membrane receptor. Ultrastructural analysis of contact regions revealed point-like interactions between hepatic microvilli and erythrocytes and no broad areas of membrane contact. When liver cells are cultivated in vitro they lose their ability to bind erythrocytes within 24 h.
hauptsatz hsatz_simple
identnr NLZ183672496
iqvoc_descriptor_title iqvoc_00000708:analysis
issn 0014-4827
journal_name Experimental Cell Research
materialart 1
package_name Elsevier
publikationsort Amsterdam
publisher Elsevier
reference 113 (1978), S. 319-325
search_space articles
shingle_author_1 Kolb, H.
Schudt, C.
Kolb-Bachofen, V.
Kolb, H.-A.
shingle_author_2 Kolb, H.
Schudt, C.
Kolb-Bachofen, V.
Kolb, H.-A.
shingle_author_3 Kolb, H.
Schudt, C.
Kolb-Bachofen, V.
Kolb, H.-A.
shingle_author_4 Kolb, H.
Schudt, C.
Kolb-Bachofen, V.
Kolb, H.-A.
shingle_catch_all_1 Kolb, H.
Schudt, C.
Kolb-Bachofen, V.
Kolb, H.-A.
Cellular recognition by rat liver cells of neuraminidase-treated erythrocytes - Demonstration and analysis of cell contacts
0014-4827
00144827
Elsevier
shingle_catch_all_2 Kolb, H.
Schudt, C.
Kolb-Bachofen, V.
Kolb, H.-A.
Cellular recognition by rat liver cells of neuraminidase-treated erythrocytes - Demonstration and analysis of cell contacts
0014-4827
00144827
Elsevier
shingle_catch_all_3 Kolb, H.
Schudt, C.
Kolb-Bachofen, V.
Kolb, H.-A.
Cellular recognition by rat liver cells of neuraminidase-treated erythrocytes - Demonstration and analysis of cell contacts
0014-4827
00144827
Elsevier
shingle_catch_all_4 Kolb, H.
Schudt, C.
Kolb-Bachofen, V.
Kolb, H.-A.
Cellular recognition by rat liver cells of neuraminidase-treated erythrocytes - Demonstration and analysis of cell contacts
0014-4827
00144827
Elsevier
shingle_title_1 Cellular recognition by rat liver cells of neuraminidase-treated erythrocytes - Demonstration and analysis of cell contacts
shingle_title_2 Cellular recognition by rat liver cells of neuraminidase-treated erythrocytes - Demonstration and analysis of cell contacts
shingle_title_3 Cellular recognition by rat liver cells of neuraminidase-treated erythrocytes - Demonstration and analysis of cell contacts
shingle_title_4 Cellular recognition by rat liver cells of neuraminidase-treated erythrocytes - Demonstration and analysis of cell contacts
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source_archive Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
timestamp 2024-05-06T08:22:24.005Z
titel Cellular recognition by rat liver cells of neuraminidase-treated erythrocytes - Demonstration and analysis of cell contacts
titel_suche Cellular recognition by rat liver cells of neuraminidase-treated erythrocytes - Demonstration and analysis of cell contacts
Freshly isolated rat liver cells adhere firmly to neuraminidase-treated rat or mouse erythrocytes but not to untreated erythrocytes. Binding between cells occurs only in the presence of calcium and is specially inhibited by d-galactose. We therefore suggest that cell adherence is mediated by a galactose-specific hepatic membrane receptor. Ultrastructural analysis of contact regions revealed point-like interactions between hepatic microvilli and erythrocytes and no broad areas of membrane contact. When liver cells are cultivated in vitro they lose their ability to bind erythrocytes within 24 h.
topic W
WW-YZ
uid nat_lic_papers_NLZ183672496